Characteristics of hospitalized patients with confirmed COVID-19 and their hospital management

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Lely Indrawati, D. Tjandrarini, Ning Sulistiyowati, Tin Afifah, Astridya Paramita, F. P. Senewe, Pandji Wibawa Dewantara
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Abstract

To determine the risk factors of mortality among hospitalized COVID-19 patients. This retrospective study used hospitalization records collected by the Indonesia Health Social Security Administrator Agency (Badan Penyelenggara Jaminan Sosial Kesehatan-BPJS Kesehatan). A total of 38277 eligible patients with confirmed COVID-19 were analyzed. The dependent variable of the study was the discharge status (death or recovery) of COVID-19. Independent variables were history of morbidity and disease-related occurrence, type of room health facilities, length of stay and demographic variables (sex, age). The analyses use bivariate and multivariate logistic regression to determine the dominating variable associated with all these variables. Of the 38 277 inpatients with PCR-confirmed COVID-19, 31051 (81.1%) were discharged and 7226 (18.9%) died. Risk of death was positively associated with older age (aOR 5.74, 95% CI 4.20-7.87 for 19-64 years old; aOR 13.75, 95% CI 9.99-18.92 for 65 years above), male sex (aOR 1.13, 95% CI 1.07-1.19), treated in ICU without ventilator (aOR 5.84, 95% CI 5.41-6.30) and had comorbid respiratory diseases (aOR 5.39, 95% CI 4.93-5.90), but negatively associated with hospital stay of 15 days or longer (aOR 0.39, 95% CI 0.36-0.43). COVID-19 related death during hospitalization was associated with duration and type of treatment, and existing medical condition among the inpatient individuals during COVID-19 pandemic in DKI Jakarta. The findings of the study suggest importance of appropriate and timely medical intervention and care.
确诊为 COVID-19 的住院患者的特征及其医院管理
确定 COVID-19 住院患者的死亡风险因素。 这项回顾性研究使用了印度尼西亚卫生社会保障局(Badan Penyelenggara Jaminan Sosial Kesehatan-BPJS Kesehatan)收集的住院记录。共分析了 38277 名确诊为 COVID-19 的合格患者。研究的因变量是 COVID-19 的出院状态(死亡或康复)。自变量为发病史和疾病相关病史、病房医疗设施类型、住院时间和人口统计学变量(性别、年龄)。分析采用双变量和多变量逻辑回归,以确定与所有这些变量相关的主导变量。 在 38 277 名经 PCR 证实感染 COVID-19 的住院病人中,31051 人(81.1%)出院,7226 人(18.9%)死亡。19)、在无呼吸机的重症监护室接受治疗(aOR 5.84,95% CI 5.41-6.30)和合并呼吸系统疾病(aOR 5.39,95% CI 4.93-5.90),但与住院 15 天或更长时间呈负相关(aOR 0.39,95% CI 0.36-0.43)。 在雅加达DKI地区COVID-19大流行期间,住院期间与COVID-19相关的死亡与治疗持续时间、治疗类型以及住院病人的现有医疗状况有关。研究结果表明,适当、及时的医疗干预和护理非常重要。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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