High Prevalence of Atrial Fibrillation Found in the Capital of Greenland When Using Continuous Electrocardiogram Monitoring: A Cross-Sectional Study

IF 2.5 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Nadja Albertsen MD, MSA , Mads Mose Jensen MD , Kunuk Lauge Koch Hansen , Michael Lynge Pedersen MD, MedScD , Stig Andersen MD, PhD , Christina Brock MSc, PhD , Sam Riahi MD, PhD
{"title":"High Prevalence of Atrial Fibrillation Found in the Capital of Greenland When Using Continuous Electrocardiogram Monitoring: A Cross-Sectional Study","authors":"Nadja Albertsen MD, MSA ,&nbsp;Mads Mose Jensen MD ,&nbsp;Kunuk Lauge Koch Hansen ,&nbsp;Michael Lynge Pedersen MD, MedScD ,&nbsp;Stig Andersen MD, PhD ,&nbsp;Christina Brock MSc, PhD ,&nbsp;Sam Riahi MD, PhD","doi":"10.1016/j.cjco.2024.03.011","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Atrial fibrillation (AF) increases the risk of conditions such as ischemic stroke, dementia, and heart failure, and early detection is crucial. In Greenland, ischemic strokes are common, and the prevalences of AF risk factors are increasing. Studies based on 30-second electrocardiograms (ECGs) and diagnosis codes so far have indicated either a low prevalence of AF or a prevalence comparable to that in other Western countries, such as Denmark. However, using short, single-point ECGs may underestimate the true prevalence, as especially paroxysmal AF can be missed. With this study, we aim to estimate the prevalence of AF using 3-5–day continuous Holter recordings among people in Nuuk, the capital of Greenland.</p></div><div><h3>Methods</h3><p>In this cross-sectional study, we estimated the prevalence of AF among the population aged ≥ 50 years in Greenland’s capital, Nuuk. We used an ePatch to record continuous ECGs for 3-5 days, and questionnaires to assess demographic data, comorbidities, medication, symptoms, and risk factors for AF.</p></div><div><h3>Results</h3><p>Of 226 participants (62% women), 21 (33% women) had either self-reported AF, AF on the recording, or both, equivalent to a prevalence of 9.3% (confidence interval [CI] 5.8-13.9). The age-stratified prevalence was 7.2% (CI 2.7-15.1) among those aged 50-59 years; 8.8% (CI 4.1-16.1) among those aged 60-69 years; and 18.2% (CI 7.0-35.5) among those aged ≥ 70 years.</p></div><div><h3>Conclusions</h3><p>This study provides a novel insight into AF prevalence in Nuuk, emphasizing the potential underestimation in previous studies. Continuous ECG monitoring revealed a higher prevalence, especially among the younger age groups, urging a reevaluation of diagnostic practices in this unique population.</p></div>","PeriodicalId":36924,"journal":{"name":"CJC Open","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589790X24001434/pdfft?md5=67992e059b63f1af83a0d2a5a29b8b15&pid=1-s2.0-S2589790X24001434-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"CJC Open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2589790X24001434","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0

Abstract

Background

Atrial fibrillation (AF) increases the risk of conditions such as ischemic stroke, dementia, and heart failure, and early detection is crucial. In Greenland, ischemic strokes are common, and the prevalences of AF risk factors are increasing. Studies based on 30-second electrocardiograms (ECGs) and diagnosis codes so far have indicated either a low prevalence of AF or a prevalence comparable to that in other Western countries, such as Denmark. However, using short, single-point ECGs may underestimate the true prevalence, as especially paroxysmal AF can be missed. With this study, we aim to estimate the prevalence of AF using 3-5–day continuous Holter recordings among people in Nuuk, the capital of Greenland.

Methods

In this cross-sectional study, we estimated the prevalence of AF among the population aged ≥ 50 years in Greenland’s capital, Nuuk. We used an ePatch to record continuous ECGs for 3-5 days, and questionnaires to assess demographic data, comorbidities, medication, symptoms, and risk factors for AF.

Results

Of 226 participants (62% women), 21 (33% women) had either self-reported AF, AF on the recording, or both, equivalent to a prevalence of 9.3% (confidence interval [CI] 5.8-13.9). The age-stratified prevalence was 7.2% (CI 2.7-15.1) among those aged 50-59 years; 8.8% (CI 4.1-16.1) among those aged 60-69 years; and 18.2% (CI 7.0-35.5) among those aged ≥ 70 years.

Conclusions

This study provides a novel insight into AF prevalence in Nuuk, emphasizing the potential underestimation in previous studies. Continuous ECG monitoring revealed a higher prevalence, especially among the younger age groups, urging a reevaluation of diagnostic practices in this unique population.

格陵兰首府使用连续心电图监测发现心房颤动发病率高:一项横断面研究
背景心房颤动(房颤)会增加缺血性中风、痴呆症和心力衰竭等疾病的风险,因此早期发现至关重要。在格陵兰岛,缺血性中风很常见,房颤风险因素的发病率也在上升。迄今为止,基于 30 秒心电图和诊断代码的研究表明,心房颤动的发病率较低,或与丹麦等其他西方国家的发病率相当。然而,使用短时间的单点心电图可能会低估真实的患病率,因为尤其是阵发性房颤可能会被漏诊。在这项研究中,我们旨在使用 3-5 天的连续 Holter 记录来估算格陵兰首府努克的房颤患病率。方法在这项横断面研究中,我们估算了格陵兰首府努克年龄≥ 50 岁人群的房颤患病率。我们使用电子血压计连续记录了 3-5 天的心电图,并通过问卷调查评估了人口统计学数据、合并症、药物治疗、症状和心房颤动的风险因素。结果在 226 名参与者(62% 为女性)中,21 人(33% 为女性)自述有心房颤动,或在记录中发现有心房颤动,或两者皆有,患病率为 9.3%(置信区间 [CI] 5.8-13.9)。按年龄划分,50-59 岁人群的患病率为 7.2%(置信区间 [CI] 2.7-15.1);60-69 岁人群的患病率为 8.8%(置信区间 [CI] 4.1-16.1);≥ 70 岁人群的患病率为 18.2%(置信区间 [CI] 7.0-35.5)。连续心电图监测显示房颤的发病率较高,尤其是在年轻群体中,因此需要对这一特殊人群的诊断方法进行重新评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CJC Open
CJC Open Medicine-Cardiology and Cardiovascular Medicine
CiteScore
3.30
自引率
0.00%
发文量
143
审稿时长
60 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信