Liposomes as Transformative Tools in Drug Delivery, Therapeutics, and Beyond

IF 0.3 Q4 PHARMACOLOGY & PHARMACY

Current Drug Therapy Pub Date : 2024-03-22 DOI:10.2174/0115748855288237240222072928

Ashish Srivastava, Anshuman Singh, Parul Srivastava, A. Wal, Pranay Wal, A. Yadav, Awani K Rai

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引用次数: 0

Abstract

Abstract: Liposomes are spherical vesicles composed of lipid bilayers that have gained significant attention in the realm of drug delivery and therapeutic applications. They offer several advantages over traditional drug delivery systems, including: -Protection of drugs from degradation and clearance -Enhanced bioavailability - Reduced systemic toxicity - Precise, site-specific drug delivery To elucidate the multifaceted aspects of liposomes, from their fundamental structure and composition to their cutting-edge applications in medicine and biotechnology. This comprehensive review was conducted through a systematic search of relevant literature on liposomes. The search was limited to English-language articles published in the past 10 years. A total of 150 articles were selected for review based on their relevance and impact. The review provides a detailed overview of the following aspects of liposomes: -Structure and composition - Mechanism of action - Targeting strategies - Preparation methods - Biomedical and biotechnological applications Liposomes are a promising drug delivery platform with the potential to revolutionize the treatment of various diseases. Their unique properties, including biocompatibility, versatility, and tunability, render them ideal for encapsulating a wide range of therapeutic agents. The review highlights the significant progress made in liposome research in recent years, paving the way for their translation into clinical practice.

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脂质体是药物输送、治疗及其他领域的变革性工具

摘要：脂质体是由脂质双层组成的球形囊泡，在药物输送和治疗应用领域备受关注。为了从脂质体的基本结构和组成到其在医学和生物技术领域的前沿应用等多方面阐明脂质体，本综述对脂质体的相关文献进行了系统检索。本综述详细概述了脂质体的以下几个方面：- 结构和组成- 作用机制- 靶向策略- 制备方法- 生物医学和生物技术应用脂质体是一种前景广阔的给药平台，有望彻底改变各种疾病的治疗方法。脂质体具有独特的特性，包括生物相容性、多功能性和可调性，是封装多种治疗药物的理想选择。这篇综述重点介绍了近年来脂质体研究取得的重大进展，为将脂质体应用于临床实践铺平了道路。

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来源期刊

Current Drug Therapy PHARMACOLOGY & PHARMACY-

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.

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