The development of chicken cerebellar cortex and the determination of AgNOR activity of the Purkinje cell nuclei

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-03-25 DOI:10.26496/bjz.2010.171

Serdar Akar, E. Sur

引用次数: 13

Abstract

In this study, the embryonic and post-hatching development of the chicken cerebellar cortex, and the number, size and area of the silver-staining nucleolus-organizer regions (AgNORs) were determined in cerebellar Purkinje cells in layer-hen (Babcock-B380) embryos and chickens. The mean transverse diameter of the Purkinje cells and their nuclei, and the mean area of the Purkinje cell nucleus and AgNOR area increased during the entire experimental period. The mean ratio of the AgNOR area to the Purkinje cell nucleus area reached its highest value at the 15th day of incubation. There was no difference between the mean AgNOR numbers per nucleus. These findings provide reference data for future studies in this and related research topics, for example for establishing AgNOR parameters and we also hope that our data will be supplemented with other techniques such as PCNA and TUNEL in the near future.

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鸡小脑皮层的发育和浦肯野细胞核 AgNOR 活性的测定

本研究测定了层雉（Babcock-B380）胚胎和鸡孵化后小脑皮层的发育情况，以及小脑浦肯野细胞核-组织区（AgNOR）的数量、大小和面积。在整个实验期间，小脑浦肯野细胞及其细胞核的平均横向直径、浦肯野细胞核的平均面积和 AgNOR 面积都在增加。AgNOR面积与浦肯野细胞核面积的平均比值在孵化第15天达到最高值。每个核的平均 AgNOR 数量之间没有差异。这些发现为今后本研究及相关研究课题的研究提供了参考数据，例如用于确定 AgNOR 参数，我们还希望在不久的将来能用 PCNA 和 TUNEL 等其他技术对我们的数据进行补充。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.