Anti-inflammatory and antimicrobial properties of some licorice metabolites

A. I. Khavkin, K. Nikolaychuk, E. V. Shreiner, M. F. Novikova, A. S. Veremenko, I. D. Levchenko, E. E. Vergunova, A. S. Tumas, P. Y. Platonova, A. Ponomarenko, I. A. Pak, E. Pokushalov
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引用次数: 0

Abstract

This article highlights the pharmacological activity of licorice metabolites of significant interest in the context of the treatment of cancer, cardiovascular, and respiratory diseases. The review details the diversity and efficacy of lichalocone, isoliquiritigenin, liquiritigenin, and other licorice metabolites that exhibit anti-inflammatory, antimicrobial, and antioxidant effects. These effects are based on the ability of licorice metabolites to regulate molecular cascades responsible for apoptosis, cell cycle, cell proliferation and many other processes. The article discusses in detail the prospects for the use of licorice metabolites in oncology, cardiology, their potential in the development of new drugs and the need for further research to determine their full therapeutic potential.
一些甘草代谢物的抗炎和抗菌特性
本文重点介绍了在治疗癌症、心血管疾病和呼吸系统疾病方面具有重要意义的甘草代谢物的药理活性。这篇综述详细介绍了lichalocone、isiquiritigenin、liquiritigenin和其他甘草代谢物的多样性和功效,它们具有抗炎、抗菌和抗氧化作用。这些作用基于甘草代谢物调节分子级联的能力,而分子级联负责细胞凋亡、细胞周期、细胞增殖和许多其他过程。文章详细讨论了甘草代谢物在肿瘤学和心脏病学中的应用前景、其在新药开发中的潜力以及进一步研究以确定其全部治疗潜力的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
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