Comparative analysis of LDF phase portraits in periodontal microcirculation among patient with type 2 diabetes mellitus

Abstract

Relevance. Periodontal diseases are among the most prevalent conditions affecting the oral cavity, often leading to tooth loss. Comorbid conditions, especially type 2 diabetes mellitus (DM2), can significantly influence the health of periodontal tissues by altering microcirculatory dynamics.Materials and methods. This study aimed to evaluate periodontal tissue health in patients with chronic periodontitis, both with and without DM2 comorbidity. Periodontal microcirculation was examined using the Laser Doppler Flowmetry (LDF) technique, specifically with a LAKK-M device (Russia). A total of 106 patients were recruited and categorized into four groups based on their DM2 status and the severity of chronic periodontitis.Results. The study revealed group-specific differences in periodontal microcirculation parameters, analyzed through nonlinear dynamics. Notably, patients with chronic periodontitis and comorbid DM2 exhibited the most significant alterations. A phase portrait analysis further delineated the microcirculation health disparities between groups.Conclusion. There were marked differences in microcirculation health among chronic periodontitis patients with and without DM2 comorbidity, as evidenced by significant changes in the nonlinear dynamics-based phase portraits.