{"title":"Prevalence of sexual dysfunction in Chinese patients with schizophrenia: a systematic review and meta-analysis.","authors":"Linghui Zhang, Yubin Chen, Yujing Sun, Yuqiu Zhou, Qi Li, Yannan Jia","doi":"10.1093/sexmed/qfae009","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>There may be a higher risk of sexual dysfunction in the schizophrenia population. China has made significant contributions to the global community of patients with schizophrenia. Currently, there is no estimation of the prevalence of sexual dysfunction in Chinese patients with schizophrenia.</p><p><strong>Aim: </strong>We conducted a meta-analysis to pool the evaluated prevalence of sexual dysfunction in Chinese patients with schizophrenia.</p><p><strong>Methods: </strong>We systematically searched PubMed, Web of Science, Embase, PsycINFO, China National Knowledge Infrastructure, China Science and Technology Journal Database, Wanfang Medical Network, and Huayi Academic Literature Database from inception to September 2023. Meta-analysis was conducted with R version 4.3.1.</p><p><strong>Outcomes: </strong>To examine the pooled prevalence of sexual dysfunctions among Chinese patients with schizophrenia.</p><p><strong>Results: </strong>In our meta-analysis, we included 16 studies with 5417 participants, among whom 1727 experienced sexual dysfunction. The results of the meta-analysis reveal that the prevalence of sexual dysfunction in Chinese patients with schizophrenia is 50.43% (95% CI, 37.86%-62.95%). Subgroup analysis results indicate that various factors-including the specific type of dysfunction, duration of illness, assessment tools, mean ages, study region, gender, research setting, marital status, publication years, and type of antipsychotics-all have a particular impact on the occurrence rate of sexual dysfunction in Chinese patients with schizophrenia. Female patients had a slightly higher prevalence of sexual dysfunction than male patients (65.22% vs 54.84%).</p><p><strong>Clinical implications: </strong>The findings of this study can be used in high-quality nursing care for the schizophrenia population, particularly for the care of specific sexual dysfunction nursing.</p><p><strong>Strengths and limitations: </strong>This meta-analysis is the first to evaluate the prevalence of sexual dysfunction in China among patients with schizophrenia. The limited number of studies is the most important limitation.</p><p><strong>Conclusions: </strong>The pooled prevalence of sexual dysfunction in Chinese patients with schizophrenia is relatively high, and the prevention and intervention of individual sexual dysfunctions in schizophrenia are advised.</p>","PeriodicalId":21782,"journal":{"name":"Sexual Medicine","volume":"12 2","pages":"qfae009"},"PeriodicalIF":2.6000,"publicationDate":"2024-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10982523/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sexual Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/sexmed/qfae009","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/4/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background: There may be a higher risk of sexual dysfunction in the schizophrenia population. China has made significant contributions to the global community of patients with schizophrenia. Currently, there is no estimation of the prevalence of sexual dysfunction in Chinese patients with schizophrenia.
Aim: We conducted a meta-analysis to pool the evaluated prevalence of sexual dysfunction in Chinese patients with schizophrenia.
Methods: We systematically searched PubMed, Web of Science, Embase, PsycINFO, China National Knowledge Infrastructure, China Science and Technology Journal Database, Wanfang Medical Network, and Huayi Academic Literature Database from inception to September 2023. Meta-analysis was conducted with R version 4.3.1.
Outcomes: To examine the pooled prevalence of sexual dysfunctions among Chinese patients with schizophrenia.
Results: In our meta-analysis, we included 16 studies with 5417 participants, among whom 1727 experienced sexual dysfunction. The results of the meta-analysis reveal that the prevalence of sexual dysfunction in Chinese patients with schizophrenia is 50.43% (95% CI, 37.86%-62.95%). Subgroup analysis results indicate that various factors-including the specific type of dysfunction, duration of illness, assessment tools, mean ages, study region, gender, research setting, marital status, publication years, and type of antipsychotics-all have a particular impact on the occurrence rate of sexual dysfunction in Chinese patients with schizophrenia. Female patients had a slightly higher prevalence of sexual dysfunction than male patients (65.22% vs 54.84%).
Clinical implications: The findings of this study can be used in high-quality nursing care for the schizophrenia population, particularly for the care of specific sexual dysfunction nursing.
Strengths and limitations: This meta-analysis is the first to evaluate the prevalence of sexual dysfunction in China among patients with schizophrenia. The limited number of studies is the most important limitation.
Conclusions: The pooled prevalence of sexual dysfunction in Chinese patients with schizophrenia is relatively high, and the prevention and intervention of individual sexual dysfunctions in schizophrenia are advised.
背景：精神分裂症患者出现性功能障碍的风险较高。中国为全球精神分裂症患者群体做出了重要贡献。目的：我们进行了一项荟萃分析，以汇集中国精神分裂症患者性功能障碍患病率的评估结果：方法：我们系统检索了PubMed、Web of Science、Embase、PsycINFO、中国国家知识基础设施、中国科技期刊数据库、万方医学网和华艺学术文献数据库（从开始到2023年9月）。使用 R 4.3.1.版本进行元分析：研究中国精神分裂症患者性功能障碍的总体患病率：在荟萃分析中，我们纳入了16项研究，共有5417名参与者，其中1727人出现性功能障碍。荟萃分析结果显示，中国精神分裂症患者的性功能障碍患病率为 50.43%（95% CI，37.86%-62.95%）。亚组分析结果表明，包括性功能障碍的具体类型、病程、评估工具、平均年龄、研究地区、性别、研究环境、婚姻状况、发表年限和抗精神病药物类型在内的各种因素都对中国精神分裂症患者性功能障碍的发生率有特殊影响。女性患者的性功能障碍发生率略高于男性患者（65.22% vs 54.84%）：本研究结果可用于精神分裂症人群的优质护理，尤其是特定性功能障碍护理：这项荟萃分析首次评估了中国精神分裂症患者性功能障碍的患病率。研究数量有限是最重要的局限性：中国精神分裂症患者性功能障碍的总体患病率较高，建议对精神分裂症患者的个别性功能障碍进行预防和干预。
期刊介绍：
Sexual Medicine is an official publication of the International Society for Sexual Medicine, and serves the field as the peer-reviewed, open access journal for rapid dissemination of multidisciplinary clinical and basic research in all areas of global sexual medicine, and particularly acts as a venue for topics of regional or sub-specialty interest. The journal is focused on issues in clinical medicine and epidemiology but also publishes basic science papers with particular relevance to specific populations. Sexual Medicine offers clinicians and researchers a rapid route to publication and the opportunity to publish in a broadly distributed and highly visible global forum. The journal publishes high quality articles from all over the world and actively seeks submissions from countries with expanding sexual medicine communities. Sexual Medicine relies on the same expert panel of editors and reviewers as The Journal of Sexual Medicine and Sexual Medicine Reviews.
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