Recalled age of myopia onset may predict risk of high adult myopia in Chinese adults.

IF 2 4区医学 Q2 OPHTHALMOLOGY

Ophthalmic Research Pub Date : 2024-03-29 DOI:10.1159/000538442

Chunjie Mao, Xiaodan Zhang, Mengyu Liao, Fengqi Zhou, Xinlei Zhu, Tian Wang, Ruotian Xie, Haokun Zhang, Tiantian Yang, Kai He, Miao Guo, Yanfang Zhu, Yi Lei, Yiming Li, Ling Yao, Bohao Cui, Yuyang Miao, Han Han, Xiao Zhao, Yinting Song, Zhiyong Sun, Jinguo Yu, Wei Zhou, Yun Zhu, Hua Yan

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引用次数: 0

Abstract

Introduction: This study aimed to investigate the relationship between age of myopia onset and high myopia and to explore if age of onset mediated the associations of high myopia with parental myopia and time spent on electronics.

Methods: This cross-sectional study enrolled 1118 myopic patients aged 18 to 40. Information was obtained via a detailed questionnaire. Multivariable logistic regression and linear regression models were utilized to assess age of onset in relation to high myopia and spherical equivalent refractive error, respectively. Structural equation models examined the mediated effect of onset age on the association between parental myopia, time spent on electronics and high myopia.

Results: An early age at myopia onset was negatively correlated with spherical equivalent refractive power. Subjects who developed myopia before the age of 12 were more likely to suffer from high myopia than those who developed myopia after the age of 15. Age of myopia onset was the strongest predictor of high myopia, with an area under the curve (AUC) in Receiver Operator Characteristic (ROC) analysis of 0.80. Additionally, age of myopia onset served as a mediator in the relationships between parental myopia, electronic device usage duration, and the onset of high myopia in adulthood.

Conclusions: Age of myopia onset might be the single best predictor for high myopia, and age at onset appeared to mediate the associations of high myopia with parental myopia and time spent on electronics.

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回忆近视发病年龄可预测中国成年人高度近视的风险。

导言：本研究旨在调查近视发病年龄与高度近视之间的关系，并探讨近视发病年龄是否能调节高度近视与父母近视和电子产品使用时间之间的关系：这项横断面研究共招募了 1118 名 18 至 40 岁的近视患者。通过详细的问卷调查获得了相关信息。多变量逻辑回归和线性回归模型分别用于评估发病年龄与高度近视和球面等效屈光不正的关系。结构方程模型研究了发病年龄对父母近视、电子产品使用时间和高度近视之间关系的中介效应：结果：近视发病年龄与球面等效屈光力呈负相关。12 岁前近视的受试者比 15 岁后近视的受试者更容易患高度近视。近视发病年龄是预测高度近视的最有力指标，其曲线下面积（AUC）在接收器特征（ROC）分析中为 0.80。此外，近视发病年龄还是父母近视、电子设备使用时间和成年后高度近视发病之间关系的中介因素：近视发病年龄可能是预测高度近视的唯一最佳指标，而近视发病年龄似乎是高度近视与父母近视和电子产品使用时间之间关系的中介因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ophthalmic Research 医学-眼科学

CiteScore

3.80

自引率

4.80%

发文量

审稿时长

6-12 weeks

期刊介绍： ''Ophthalmic Research'' features original papers and reviews reporting on translational and clinical studies. Authors from throughout the world cover research topics on every field in connection with physical, physiologic, pharmacological, biochemical and molecular biological aspects of ophthalmology. This journal also aims to provide a record of international clinical research for both researchers and clinicians in ophthalmology. Finally, the transfer of information from fundamental research to clinical research and clinical practice is particularly welcome.