Which adolescents are more likely to complete home-based sleep manipulation trials?

IF 3.4 2区医学 Q2 CLINICAL NEUROLOGY

Sleep Health Pub Date : 2024-06-01 DOI:10.1016/j.sleh.2024.01.010

Andrea L. Fidler PhD, MPH , Gargi Rajput BS , Nanhua Zhang PhD , Dean W. Beebe PhD, ABPP

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引用次数: 0

Abstract

Objectives

Attrition and nonadherence are common concerns that can distort findings in clinical trials. This study examines the potential for systematic attrition in the largest sample to date of adolescents undergoing sleep manipulation.

Methods

Using pooled data across two trials involving 242 adolescents, a cumulative logistic regression tested whether demographics and baseline sleep predicted study completion/adherence.

Results

Race, a composite measure of socioeconomic status, and its elements (e.g., income, education) individually predicted completion/adherence. When entered concurrently into a multivariate predictive model, only socioeconomic status and study (trial A vs. B) were significant. Adolescents from households with higher socioeconomic status were more likely to complete or adhere to the protocol than those from households with lower socioeconomic status, p < .001.

Conclusions

Systematic attrition in sleep manipulation research could distort conclusions about under-resourced groups. Future sleep trials should intentionally measure systemic/structural factors and adopt strategies to recruit and retain participants from various backgrounds.

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哪些青少年更有可能完成家庭睡眠控制试验？

目的：减员和不坚持是临床试验中常见的问题，可能会扭曲试验结果。本研究在迄今为止最大的青少年睡眠操作样本中研究了系统性减员的可能性：利用涉及 242 名青少年的两项试验的汇总数据，采用累积逻辑回归法检验了人口统计学和基线睡眠是否能预测研究的完成/坚持情况：结果：种族、社会经济地位的综合衡量标准及其要素（如收入、教育程度）可单独预测研究的完成度/依从性。当同时输入多变量预测模型时，只有社会经济地位和研究（试验 A 与试验 B）具有显著性。与来自社会经济地位较低家庭的青少年相比，来自社会经济地位较高家庭的青少年更有可能完成或坚持方案，P 结论：睡眠操控研究中的系统性减员可能会扭曲有关资源不足群体的结论。未来的睡眠试验应有意识地测量系统性/结构性因素，并采取策略招募和留住来自不同背景的参与者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sleep Health CLINICAL NEUROLOGY-

CiteScore

6.30

自引率

9.80%

发文量

114

审稿时长

54 days

期刊介绍： Sleep Health Journal of the National Sleep Foundation is a multidisciplinary journal that explores sleep''s role in population health and elucidates the social science perspective on sleep and health. Aligned with the National Sleep Foundation''s global authoritative, evidence-based voice for sleep health, the journal serves as the foremost publication for manuscripts that advance the sleep health of all members of society.The scope of the journal extends across diverse sleep-related fields, including anthropology, education, health services research, human development, international health, law, mental health, nursing, nutrition, psychology, public health, public policy, fatigue management, transportation, social work, and sociology. The journal welcomes original research articles, review articles, brief reports, special articles, letters to the editor, editorials, and commentaries.