Appendiceal mucinous neoplasm in adolescence: Diagnosis, management, and surveillance.

JPGN reports Pub Date : 2023-12-27 eCollection Date: 2024-02-01 DOI:10.1002/jpr3.12017
Andrew Farrar, Paola Blanco, Abigail Fabbrini, Lindsey Armstrong, Jonathan Metts, Hector Monforte, Sara Karjoo, Paul Danielson, Michael Wilsey
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Abstract

This case report describes a 17-year-old patient with a low-grade appendiceal mucinous neoplasm. The patient presented with non-bloody diarrhea, abdominal pain, and weight loss. A colonoscopy revealed a cecal polypoid mass that required laparoscopic surgery. The residual appendix was dilated with myxoglobulosis and histopathology confirmed the diagnosis of a low-grade appendiceal mucinous neoplasm staged pT3Nx. The potential risk of pseudomyxoma peritonei is a serious complication of these tumors. Surveillance plans include computed tomography abdomen and pelvis, and tumor markers every 6 months for the next 2 years. This case highlights the importance of considering appendiceal malignancy in patients with abdominal pain and weight loss, despite the rarity of the disease. It also emphasizes the need for careful monitoring due to the possible complications associated with these tumors. Treatment and prognosis for appendiceal neoplasms depend on the histopathologic characteristics, tumor-nodes-metastasis stage, tumor grade, and presence of peritoneal disease.

青春期阑尾粘液瘤:诊断、管理和监控。
本病例报告描述了一名患有低级别阑尾粘液瘤的 17 岁患者。患者出现非血性腹泻、腹痛和体重减轻。结肠镜检查发现了盲肠息肉样肿块,需要进行腹腔镜手术。残余阑尾扩张并伴有肌球蛋白增多,组织病理学确诊为低级别阑尾粘液瘤,分期为 pT3Nx。假性腹膜肌瘤的潜在风险是这类肿瘤的严重并发症。监控计划包括腹部和盆腔计算机断层扫描,以及在未来两年内每 6 个月进行一次肿瘤标志物检查。本病例强调了在腹痛和体重减轻的患者中考虑阑尾恶性肿瘤的重要性,尽管这种疾病非常罕见。该病例还强调,由于这些肿瘤可能引起并发症,因此需要进行仔细监测。阑尾肿瘤的治疗和预后取决于组织病理学特征、肿瘤-结节-转移分期、肿瘤分级以及是否存在腹膜疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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