Risk factors for unexpected infant death among very premature infants in France

IF 1.3 4区医学 Q3 PEDIATRICS

Archives De Pediatrie Pub Date : 2024-04-01 DOI:10.1016/j.arcped.2023.12.003

Anne-Laure Bourneuf , Estelle Le Pabic , Sophie de Visme , Karine Levieux , Patrick Pladys

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引用次数: 0

Abstract

Background

Prematurity is one of the risk factors for sudden unexpected infant death (SUID), a phenomenon that remains poorly explained.

Materials and methods

The analysis of specific factors associated with SUID among very premature infants (VPI) was performed through a retrospective review of data collected in the French SUID registry from May 2015 to December 2018. The factors associated with SUID among VPI were compared with those observed among full-term infants (FTI). Results are expressed as means (standard deviation [SD]) or medians (interquartile range [IQR)].

Results

During the study period, 719 cases of SUID were included in the registry, 36 (incidence: 0.60 ‰) of which involved VPI (gestational age: 29.2 [2] weeks, 1157 [364]) g] and 313 (0.18 ‰) involved FTI (gestational age: 40 [0.8] weeks, 3298 [452] g). The infants’ postnatal age at the time of death was similar in the two groups: 15.5 (12.2–21.8) vs. 14.5 (7.1–23.4) weeks. We observed low breastfeeding rates and a high proportion of fathers with no occupation or unemployment status among the VPI compared to the FTI group (31% vs. 55 %, p = 0.01 and 32% vs. 13 %, p = 0.05, respectively). Among the VPI, only 52 % were in supine position, and 29 % were lying prone at the time of the SUID (compared to 63 % and 17 %, respectively, in the FTI group).

Conclusion

This study confirms prematurity as a risk factor for SUID with no difference in the SUID-specific risk factors studied except for breastfeeding and socioeconomic status of the fathers. VPI and FTI died at similar chronological ages with a high proportion of infants dying in prone position. These results argue for reinforcement of prevention strategies in cases of prematurity.

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法国早产儿意外死亡的风险因素。

背景：早产是婴儿意外猝死（SUID）的风险因素之一，这一现象至今仍未得到很好的解释：通过对2015年5月至2018年12月期间法国SUID登记处收集的数据进行回顾性审查，分析了与极早产儿（VPI）SUID相关的具体因素。将极早产儿（VPI）中与 SUID 相关的因素与足月儿（FTI）中观察到的因素进行了比较。结果以均值（标准差[SD]）或中位数（四分位距[IQR]）表示：在研究期间，共有 719 例 SUID 病例被纳入登记册，其中 36 例（发病率：0.60 ‰）涉及 VPI（胎龄：29.2 [2] 周，体重 1157 [364] g），313 例（0.18 ‰）涉及 FTI（胎龄：40 [0.8] 周，体重 3298 [452] g）。两组婴儿死亡时的产后年龄相似：15.5（12.2-21.8）周 vs 14.5（7.1-23.4）周。与快速道行动组相比，我们发现 VPI 组的母乳喂养率较低，无职业或失业状况的父亲比例较高（分别为 31% 对 55%，p = 0.01 和 32% 对 13%，p = 0.05）。在 VPI 中，只有 52% 的人在 SUID 时处于仰卧位，29% 的人处于俯卧位（而在 FTI 组中分别为 63% 和 17%）：本研究证实早产是导致 SUID 的一个风险因素，除了母乳喂养和父亲的社会经济地位外，其他特定的 SUID 风险因素并无差异。VPI组和FTI组婴儿的死亡年龄相似，但俯卧位死亡的比例较高。这些结果表明，应加强早产儿的预防策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives De Pediatrie 医学-小儿科

CiteScore

2.80

自引率

5.60%

发文量

106

审稿时长

24.1 weeks

期刊介绍： Archives de Pédiatrie publishes in English original Research papers, Review articles, Short communications, Practice guidelines, Editorials and Letters in all fields relevant to pediatrics. Eight issues of Archives de Pédiatrie are released annually, as well as supplementary and special editions to complete these regular issues. All manuscripts submitted to the journal are subjected to peer review by international experts, and must: Be written in excellent English, clear and easy to understand, precise and concise; Bring new, interesting, valid information - and improve clinical care or guide future research; Be solely the work of the author(s) stated; Not have been previously published elsewhere and not be under consideration by another journal; Be in accordance with the journal''s Guide for Authors'' instructions: manuscripts that fail to comply with these rules may be returned to the authors without being reviewed. Under no circumstances does the journal guarantee publication before the editorial board makes its final decision. Archives de Pédiatrie is the official publication of the French Society of Pediatrics.