Long-term outcome of minor salivary gland transplantation for pediatric congenital alacrimia

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-06-01 DOI:10.1016/j.jaapos.2024.103903

Ananya Sudhir Nibandhe MBBS, DNB , Bhupesh Bagga MBBS, MS

引用次数: 0

Abstract

A 3-year-old boy presented with repeated episodes of corneal erosions and ulceration and absence of tear secretion since birth. Examination under anesthesia revealed a dry ocular surface, with corneal scarring and vascularization. Computed tomography of the orbit showed complete absence of lacrimal glands bilaterally. Minor salivary gland transplantation was performed in the right eye, which was more severely affected. This procedure has been used to manage severe dry eyes but not previously for congenital alacrimia. On long-term follow-up, 5 years after surgery, we observed considerable improvement in the photophobia, corneal transparency, and neovascularization.

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小儿先天性唾液腺缺失症小唾液腺移植的长期疗效。

一名 3 岁的男孩自出生以来就反复出现角膜糜烂和溃疡，并且没有泪液分泌。在麻醉状态下进行的检查发现，他的眼表干燥，角膜上有瘢痕和血管。眼眶计算机断层扫描显示双侧泪腺完全缺失。患者的右眼受到的影响更为严重，因此对右眼进行了轻微的唾液腺移植手术。这种手术曾被用于治疗严重的干眼症，但以前从未用于治疗先天性白内障。在术后 5 年的长期随访中，我们观察到患者的畏光、角膜透明度和新生血管均有显著改善。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.