Does the Incorporation of Graphene Oxide into PMMA Influence its Antimicrobial Activity?

IF 1.1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

European Journal of Prosthodontics and Restorative Dentistry Pub Date : 2024-09-01 DOI:10.1922/EJPRD_2651Ferreira07

I Ferreira, B D Sahm, O L Alves, J A M Agnelli, A C Dos Reis

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引用次数: 0

Abstract

Introduction: The increase in infectious diseases mediated by oral bacteria has been one of the most potent threats to human health, specifically to the elderly. Researchers seek to incorporate antimicrobial nanomaterials into PMMA to control the colonization of microorganisms and reduce deadly diseases.

Objective: To conduct a systematic review to answer the question: "Does graphene oxide incorporated into polymethylmethacrylate influence its antimicrobial activity?"

Methods: The electronic search was performed in PubMed, Embase, Web of Science, Scopus, and Google Scholar databases, and articles published until October 2021 were selected. The search terms were: ("acrylic resin" OR PMMA) AND (graphene OR "oxide graphene") AND (antimicrobial OR antibacterial OR "anti-infective agent"). The risk of bias analysis of the articles was performed using the quasi-experimental study assessment tool adapted from the JBI.

Results: Two hundred and fifty-nine articles were found in the databases. After removing the duplicates, 245 were analyzed by title and abstract. Of these, 06 were selected for full reading, of which 03 met the eligibility criteria and were included in this systematic review.

Conclusion: This systematic review's findings can infer that the incorporation of graphene in the form of graphene-based coatings to PMMA showed antimicrobial effectiveness.

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在 PMMA 中加入氧化石墨烯是否会影响其抗菌活性？

介绍：由口腔细菌引发的传染病日益增多，这已成为人类健康，特别是老年人健康的最大威胁之一。研究人员试图在 PMMA 中加入抗菌纳米材料，以控制微生物的定植，减少致命疾病：进行系统综述，回答以下问题"目的：对以下问题进行系统综述："聚甲基丙烯酸甲酯中加入氧化石墨烯是否会影响其抗菌活性？在 PubMed、Embase、Web of Science、Scopus 和 Google Scholar 数据库中进行电子检索，选择 2021 年 10 月之前发表的文章。检索词为(丙烯酸树脂 "或 "PMMA"）和（石墨烯或 "氧化石墨烯"）和（抗菌或抗菌剂或 "抗感染剂"）。使用改编自 JBI 的准实验研究评估工具对文章进行了偏倚风险分析：结果：在数据库中找到 259 篇文章。在删除重复文章后，根据标题和摘要对 245 篇文章进行了分析。其中，06 篇被选中进行全文阅读，03 篇符合资格标准，被纳入本系统综述：本系统综述的研究结果可以推断出，将石墨烯以石墨烯基涂层的形式加入 PMMA 中具有抗菌效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Prosthodontics and Restorative Dentistry DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

2.30

自引率

7.70%

发文量

期刊介绍： The European Journal of Prosthodontics and Restorative Dentistry is published quarterly and includes clinical and research articles in subjects such as prosthodontics, operative dentistry, implantology, endodontics, periodontics and dental materials.