High fluence in laser stapedotomy aggravates transient subjective dizziness.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-02-01 Epub Date: 2024-03-28 DOI:10.1080/00016489.2024.2329287

Yoshie Mizoguchi, Taro Fujikawa, Yoshiyuki Kawashima, Taku Ito, Ken Kitamura, Yoshihiro Noguchi, Masatoki Takahashi, Keiji Honda, Takamori Takeda, Takeshi Tsutsumi

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引用次数: 0

Abstract

Background: Laser fenestration in stapedotomy has thermal effect to the vestibule.

Aims/objectives: To evaluate the role of energy density (fluence) in the severity of postoperative vestibular symptoms.

Materials and methods: The retrospective chart-review study included 84 patients with otosclerosis that underwent primary laser stapedotomy. Surgical outcomes, including nystagmus, and subjective vestibular symptoms during one-month follow-up, were compared between potassium titanyl phosphate (KTP) and CO₂ laser. According to this study and literature, we assessed the relationship between laser parameters and the incidence of persistent vestibular symptoms lasting more than one week after surgery.

Results: The KTP and CO₂ laser group included 48 and 36 patients, respectively. Fluence was different between the KTP (637 J/cm²) and CO₂ (141 J/cm²) laser (p < .001). The KTP group showed gradual decrease in dizziness during one-month observation period, while the CO₂ group exhibited a steep recovery curve in the first postoperative week (9 and 4 d of duration, respectively). The incidence of persistent vestibular symptoms was correlated with both fluence (r = 0.80, p = .01) and spot size (r = -0.74, p = .01).

Conclusions and significance: Appropriate setting of parameters with lower fluence is desirable for the efficiency and safety of laser stapedotomy.Abbreviations: ABG: air-bone gap; SD: standard deviation.

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激光镫骨切除术的高通量会加重短暂的主观眩晕。

背景：镫骨切除术中的激光穿孔会对前庭产生热效应：评估能量密度（通量）对术后前庭症状严重程度的影响：这项回顾性图表审查研究包括84名接受了初级激光镫骨切除术的耳硬化症患者。比较了磷酸钛钾（KTP）和二氧化碳激光的手术效果，包括眼震和一个月随访期间的主观前庭症状。根据这项研究和文献，我们评估了激光参数与术后持续一周以上的前庭症状发生率之间的关系：KTP和CO2激光组分别有48和36名患者。KTP（637 J/cm2）和 CO2（141 J/cm2）激光的通量不同（p 2），KTP 组和 CO2 组在术后第一周表现出陡峭的恢复曲线（分别持续 9 天和 4 天）。持续性前庭症状的发生率与通量（r = 0.80，p = .01）和光斑大小（r = -0.74，p = .01）相关：结论和意义：为了提高激光镫骨切除术的效率和安全性，适当设置较低的通量参数是可取的：缩写：ABG：气-骨间隙；SD：标准偏差。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.