Assessment of Microvascular Changes After Rhegmatogenous Retinal Detachment Repair Using Wide-Field Swept-Source Optical Coherence Tomography Angiography.

IF 0.9 4区医学 Q4 OPHTHALMOLOGY

Ophthalmic surgery, lasers & imaging retina Pub Date : 2024-06-01 Epub Date: 2024-03-02 DOI:10.3928/23258160-20240130-01

Rachel Tandias, Itika Garg, Margaret J Duich, Filippos Vingopoulos, Raviv Katz, Rebecca Zeng, Leo A Kim, Deeba Husain, Dean Eliott, Nimesh A Patel, John B Miller, Rachel Tandias, Itika Garg

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引用次数: 0

Abstract

Background and objective: Our objective was to evaluate retinal microvascular changes and visual outcomes following rhegmatogenous retinal detachment (RRD) repair using wide-field swept-source optical coherence tomography angiography (WF SS-OCTA).

Patients and methods: The study included 116 eyes of 111 patients with macula-off (n = 68) or macula-on (n = 48) RRD treated with a single successful procedure, 79 fellow eyes, and 183 eyes of control patients imaged with WF SS-OCTA (3 ×3, 6 ×6, and 12 ×12 mm images). Mixed-effects multiple linear regression models were used for statistical analysis.

Results: Vessel density (VD) and vessel skeletonized density (VSD) of the superficial capillary plexus (3 ×3 mm scans) and full-thickness retina (12 ×12 mm) were significantly reduced in RRD eyes compared to fellow and control eyes. Decreased VSD and VD in all layers (3 ×3 mm and 6 ×6 mm) were significantly associated with greater preoperative extent of retinal detachment (P < 0.05) and poorer postoperative best-corrected visual acuity (BCVA) in RRD eyes (P < 0.05). Macula-off status was associated with increased foveal avascular zone irregularity (12 ×12 mm, P = 0.02).

Conclusions: Decreased VD on WF SS-OCTA is associated with poorer postoperative BCVA following RRD repair. [Ophthalmic Surg Lasers Imaging Retina 2024;55:310-317.].

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利用宽视场扫源光学相干断层扫描血管造影术评估流变性视网膜脱离修复术后的微血管变化

背景和目的：我们的目的是使用宽视场扫源光学相干断层血管成像（WF SS-OCTA）评估流变性视网膜脱离（RRD）修复后视网膜微血管的变化和视觉效果：研究对象包括111名黄斑脱落型（68人）或黄斑开启型（48人）RRD患者的116只眼睛（单次手术成功）、79只同侧眼睛以及183只用WF SS-OCTA（3×3、6×6和12×12 mm图像）成像的对照组眼睛。统计分析采用混合效应多元线性回归模型：结果：与同侧眼和对照眼相比，RRD 眼表浅毛细血管丛（3 ×3 mm 扫描）和全厚视网膜（12 ×12 mm）的血管密度（VD）和血管骨架密度（VSD）明显降低。各层（3 ×3 mm 和 6 ×6 mm）VSD 和 VD 的减少与 RRD 眼术前视网膜脱离范围更大（P < 0.05）和术后最佳矫正视力（BCVA）更差（P < 0.05）显著相关。黄斑脱落状态与眼窝血管区不规则度增加有关（12 ×12 mm，P = 0.02）：结论：WF SS-OCTA 上的 VD 减少与 RRD 修复术后 BCVA 较差有关。[眼科手术激光成像视网膜2024;55:XX-XX]。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ophthalmic surgery, lasers & imaging retina OPHTHALMOLOGY-SURGERY

CiteScore

1.80

自引率

0.00%

发文量

期刊介绍： OSLI Retina focuses exclusively on retinal diseases, surgery and pharmacotherapy. OSLI Retina will offer an expedited submission to publication effort of peer-reviewed clinical science and case report articles. The front of the journal offers practical clinical and practice management features and columns specific to retina specialists. In sum, readers will find important peer-reviewed retina articles and the latest findings in techniques and science, as well as informative business and practice management features in one journal.