Clinical significance of posterior expansion of the utricular endolymphatic space.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-02-01 Epub Date: 2024-03-27 DOI:10.1080/00016489.2024.2329783

Hideyuki Kaida, Tadao Yoshida, Satofumi Sugimoto, Masumi Kobayashi, Shinji Naganawa, Michihiko Sone

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Abstract

Background: Posterior expansion of the utricular endolymphatic space (ES) is a finding occasionally observed, and often occurs in bilateral ears. The clinical significance of posterior expansion of the utricular ES is not clear.

Objectives: To investigate the clinical significance of posterior expansion of the utricular ES detected on magnetic resonance imaging (MRI).

Materials and methods: Among 957 patients who underwent contrast-enhanced MRI to investigate the presence of endolymphatic hydrops (EH), clinical findings in cases with posterior expansion of the utricular ES were evaluated and the significance of their existence is considered.

Results: Posterior expansion of the utricular ES was detected in 30 ears from 20 cases (7 males, 13 females; mean age 48.7 years). The ears with posterior expansion had a significantly lower incidence of vestibular EH than those without, and this tendency was more prominent in cases in bilateral ears. Some cases with posterior expansion had vestibular symptoms and were diagnosed with Ménière's disease, although EH was not detected in their vestibules.

Conclusion and significance: Posterior expansion of the utricular ES was associated with Ménière's disease without vestibular EH. Posterior expansion of the utricular ES might not be associated with the formation of EH but may occur independently.

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子宫内淋巴间隙后方扩张的临床意义。

背景：偶尔会观察到宫腔内淋巴间隙（ES）后方扩张的现象，通常发生在双耳。子宫内淋巴间隙（ES）后方扩张的临床意义尚不明确：研究磁共振成像（MRI）中发现的宫腔内淋巴间隙（ES）后方扩张的临床意义：在 957 例接受对比增强 MRI 检查以确定是否存在内淋巴水肿（EH）的患者中，评估子宫 ES 后方扩张病例的临床表现，并考虑其存在的意义：结果：在 20 个病例（7 男 13 女；平均年龄 48.7 岁）的 30 个耳朵中发现了子宫 ES 后方扩张。耳后膨出者的前庭EH发生率明显低于无前庭EH者，这种趋势在双耳病例中更为突出。一些有耳后扩张的病例有前庭症状并被诊断为梅尼埃病，尽管在他们的前庭未检测到 EH：结论和意义：子宫ES后膨出与梅尼埃病有关，但没有前庭EH。子宫 ES 后方扩张可能与 EH 的形成无关，但可能单独发生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.