[Associations between components of metabolic syndrome and cognitive impairment in patients with schizophrenia].

Q3 Medicine

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova Pub Date : 2024-01-01 DOI:10.17116/jnevro202412403182

E G Kornetova, S A Galkin, I A Mednova, V V Tsiguntsev, A S Boiko, A N Kornetov, S A Ivanova, N A Bokhan

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引用次数: 0

Abstract

Objective: To study the relationship between the individual components of the metabolic syndrome and cognitive dysfunction in patients with schizophrenia.

Material and methods: A total of 133 patients with schizophrenia were examined. To assess cognitive functioning, the Brief Assessment of Cognition in Schizophrenia (BACS) was used. The components of the metabolic syndrome were determined in accordance with the criteria of the International Diabetes Federation.

Results: Hyperglycemia in patients with schizophrenia led to a decrease in cognitive functioning in two domains: verbal fluency (β=-10.67; p=0.019) and attention stability (β=-9.519; p=0.043). Abdominal obesity was associated with lower indicators of executive functions (β=-8.856; p=0.026).

Conclusion: It is assumed that drug treatment of some components of the metabolic syndrome may affect cognitive functions in patients with schizophrenia.

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[精神分裂症患者代谢综合征成分与认知障碍之间的关系]。

目的：研究精神分裂症患者代谢综合征的各个组成部分与认知功能障碍之间的关系：研究精神分裂症患者代谢综合征的各个组成部分与认知功能障碍之间的关系：共调查了 133 名精神分裂症患者。为了评估认知功能，使用了精神分裂症认知简评（BACS）。代谢综合征的组成部分是根据国际糖尿病联合会的标准确定的：结果：精神分裂症患者的高血糖会导致两个领域的认知功能下降：语言流畅性（β=-10.67；P=0.019）和注意力稳定性（β=-9.519；P=0.043）。腹部肥胖与较低的执行功能指标相关（β=-8.856；p=0.026）：推测药物治疗代谢综合征的某些成分可能会影响精神分裂症患者的认知功能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova 医学-精神病学

CiteScore

1.10

自引率

0.00%

发文量

287

审稿时长

3-6 weeks

期刊介绍： Одно из старейших медицинских изданий России, основанное в 1901 году. Создание журнала связано с именами выдающихся деятелей отечественной медицины, вошедших в историю мировой психиатрии и неврологии, – С.С. Корсакова и А.Я. Кожевникова. Широкий диапазон предлагаемых журналом материалов и разнообразие форм их представления привлекают внимание научных работников и врачей, опытных и начинающих медиков, причем не только неврологов и психиатров, но и специалистов смежных областей медицины.