The effect of ibuprofen sustained release oral premedication on intraoperative and postoperative pain: A randomised clinical trial

IF 1.3 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Australian Endodontic Journal Pub Date : 2024-03-25 DOI:10.1111/aej.12839

Mariam Ahmed Hossam BDS, Alaa Abdelsalam El Baz BDS, MSc, PhD, Sang Won Kwak DDS, MS, PhD, Hyeon-Cheol Kim DDS, MS, PhD, Mohamed Mohsen Abielhassan BDS, MSc, PhD

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引用次数: 0

Abstract

The aim of this study was to assess the effect of ibuprofen sustained release (SR) oral premedication on the efficacy of buccal infiltration (BI) with intraoperative and postoperative pain after single-visit root canal treatment. Sixty patients diagnosed with symptomatic irreversible pulpitis and apical periodontitis in mandibular molar were divided into two groups. Group SR received ibuprofen SR 800 mg and group PL received placebo capsule 1 h before 3.6 mL articaine BI injection. Pain was recorded using a modified visual analogue scale and postoperatively at intervals 6, 24 and 48 h. Group SR showed a significantly higher anaesthetic success rate (73.3%) compared to group PL (46.7%) (p < 0.05). Intraoperative and postoperative pain was significantly higher in group PL compared to group SR (p < 0.05). Premedication of ibuprofen SR improved the efficacy of primary BI in mandibular molars with symptomatic irreversible pulpitis and decreased postoperative pain at 6 and 48 h.

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布洛芬缓释口服预处理对术中和术后疼痛的影响：随机临床试验。

本研究旨在评估布洛芬缓释剂（SR）口服预处理对单次根管治疗后颊面浸润（BI）术中和术后疼痛疗效的影响。将 60 名被诊断为下颌磨牙无症状不可逆牙髓炎和根尖牙周炎的患者分为两组。SR 组在注射 3.6 毫升青蒿素 BI 前 1 小时服用布洛芬 SR 800 毫克，PL 组服用安慰剂胶囊。使用改良视觉模拟量表记录疼痛情况，并在术后 6、24 和 48 h 间隔时间进行记录。SR 组的麻醉成功率（73.3%）明显高于 PL 组（46.7%）（p

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来源期刊

Australian Endodontic Journal DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.50

自引率

6.20%

发文量

审稿时长

>12 weeks

期刊介绍： The Australian Endodontic Journal provides a forum for communication in the different fields that encompass endodontics for all specialists and dentists with an interest in the morphology, physiology, and pathology of the human tooth, in particular the dental pulp, root and peri-radicular tissues. The Journal features regular clinical updates, research reports and case reports from authors worldwide, and also publishes meeting abstracts, society news and historical endodontic glimpses. The Australian Endodontic Journal is a publication for dentists in general and specialist practice devoted solely to endodontics. It aims to promote communication in the different fields that encompass endodontics for those dentists who have a special interest in endodontics.