Retinal Changes in Patients With Covid-19 and Different Expressiveness of Metabolic Changes.

Q4 Medicine

Ceska a Slovenska Oftalmologie Pub Date : 2024-01-01 DOI:10.31348/2024/12

Kateryna Hutsaliuk, Nataliia Skalska, Nadiia Ulianova

{"title":"Retinal Changes in Patients With Covid-19 and Different Expressiveness of Metabolic Changes.","authors":"Kateryna Hutsaliuk, Nataliia Skalska, Nadiia Ulianova","doi":"10.31348/2024/12","DOIUrl":null,"url":null,"abstract":"Aims: To study the relationship between the severity of COVID-induced metabolic changes and the structure and frequency of retinal changes, according to funduscopy data in patients with different clinical courses of COVID-19.Materials and methods: 117 patients with COVID-19 were examined. While examining patients, severity of the course of COVID-19, the expressiveness of changes in the metabolic status were determined; fundus image registration was performed with portable fundus cameras Pictor Plus Fundus Camera and VistaView (Volk Optical).Results: As a result of the research, retinal changes were found in 49 (41.9 %) patients with COVID-19. In 8 (16.3 %) cases, clinically significant (vitreous hemorrhage, prethrombosis of the central retinal vein or branches of the central retinal vein, thrombosis of the central retinal vein or branches of the central retinal vein) COVID-induced retinal and ophthalmological changes were observed, which caused a decrease in visual acuity. In 41 (83.7 %) cases, clinically insignificant changes (cotton wool spots, narrowed retinal vessels, intraretinal and petechial hemorrhages, tortuosity and dilatation of retinal venules) COVID-induced retinal changes were observed. Clinically significant retinal changes occur in patients with a statistically significantly higher level of D-dimer and a greater percentage of lung parenchyma lesion than in the group of patients with clinically insignificant retinal changes (p < 0.05).Conclusions: The structure of retinal changes in patients with COVID-19 correlates with the severity of the clinical course of the disease and changes in the metabolic status of patients. Metabolic changes are correlated with retinal changes and can be predictive for preventing general vascular complications in COVID-19.","PeriodicalId":39839,"journal":{"name":"Ceska a Slovenska Oftalmologie","volume":"80 Ahead of print","pages":"156-166"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ceska a Slovenska Oftalmologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31348/2024/12","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Aims: To study the relationship between the severity of COVID-induced metabolic changes and the structure and frequency of retinal changes, according to funduscopy data in patients with different clinical courses of COVID-19.

Materials and methods: 117 patients with COVID-19 were examined. While examining patients, severity of the course of COVID-19, the expressiveness of changes in the metabolic status were determined; fundus image registration was performed with portable fundus cameras Pictor Plus Fundus Camera and VistaView (Volk Optical).

Results: As a result of the research, retinal changes were found in 49 (41.9 %) patients with COVID-19. In 8 (16.3 %) cases, clinically significant (vitreous hemorrhage, prethrombosis of the central retinal vein or branches of the central retinal vein, thrombosis of the central retinal vein or branches of the central retinal vein) COVID-induced retinal and ophthalmological changes were observed, which caused a decrease in visual acuity. In 41 (83.7 %) cases, clinically insignificant changes (cotton wool spots, narrowed retinal vessels, intraretinal and petechial hemorrhages, tortuosity and dilatation of retinal venules) COVID-induced retinal changes were observed. Clinically significant retinal changes occur in patients with a statistically significantly higher level of D-dimer and a greater percentage of lung parenchyma lesion than in the group of patients with clinically insignificant retinal changes (p < 0.05).

Conclusions: The structure of retinal changes in patients with COVID-19 correlates with the severity of the clinical course of the disease and changes in the metabolic status of patients. Metabolic changes are correlated with retinal changes and can be predictive for preventing general vascular complications in COVID-19.

查看原文本刊更多论文

Covid-19患者的视网膜变化及新陈代谢变化的不同表现形式。

目的：根据不同临床病程的 COVID-19 患者的眼底检查数据，研究 COVID 引起的代谢变化的严重程度与视网膜变化的结构和频率之间的关系。在对患者进行检查时，确定了 COVID-19 病程的严重程度、代谢状态变化的表现力；使用便携式眼底照相机 Pictor Plus Fundus Camera 和 VistaView（Volk Optical）进行了眼底图像注册：研究结果显示，49 名（41.9%）COVID-19 患者的视网膜发生了变化。在 8 例（16.3%）患者中，观察到了有临床意义的（玻璃体出血、视网膜中央静脉或视网膜中央静脉分支血栓形成前、视网膜中央静脉或视网膜中央静脉分支血栓形成）COVID 引起的视网膜和眼科变化，这些变化导致视力下降。在 41 例（83.7%）病例中，观察到临床上不明显的 COVID 引起的视网膜变化（棉絮斑、视网膜血管狭窄、视网膜内出血和瘀斑、视网膜静脉迂曲和扩张）。与视网膜变化不明显的患者组相比，D-二聚体水平较高且肺实质病变比例较大的患者视网膜变化明显，具有统计学意义（p <0.05）： COVID-19患者视网膜变化的结构与疾病临床过程的严重程度和患者代谢状况的变化相关。新陈代谢的变化与视网膜的变化相关，对预防 COVID-19 全身血管并发症具有预测作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Ceska a Slovenska Oftalmologie Medicine-Ophthalmology

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： - Redakce přijímá pouze práce vyhovující po odborné stránce, které jsou na odpovídající profesionální a formální úrovni. - Uveřejněná práce se stává majetkem časopisu, přetisknout její část nebo obrázek lze jen s citací původu. - Rukopis zasílejte v originále a dobře čitelné kopii (je nutná také kopie tabulek, legend, podle možnosti i obrázků). - Listy číslujte v pravém horním rohu a spojujte svorkou, nesešívejte. Přijímáme práce psané na jedné straně kvalitního bílého nelesklého papíru formátu A4 (neprůklepový) na psacím stroji nebo počítači s obvyklými typy.