BIOSURFACTANTS: SUSTAINABLE ALTERNATIVE TO SYNTHETIC SURFACTANTS AND THEIR APPLICATIONS

Praveena Poomalai, Janesha Krishnan, Ashwin Ravichandran, Raman Sureshkumar
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Abstract

Biosurfactants are surface active agents produced by microorganisms, which help reduce surface or interfacial tension between two immiscible liquids like oil and water. In recent years, Due to their environmentally friendly nature and wide range of applications in various industries, they can act as a sustainable alternative to synthetic surfactants. This review article provides an overview of biosurfactants, emphasizing their need for biosurfactants, the production process, and their classification based on molecular weight, charge, and the microorganism they derived. The advantages include biodegradability, biocompatibility, low toxicity, surface activity, and specificity, and various areas where the biosurfactant used are emulsification, thermal stability, pH stability, wetting ability, foaming ability, and spreadability. Research on using biosurfactants in various formulations like nanoparticles, liposomes, transdermal application, nanoemulsion, and nanocapsules is also highlighted in this review to support its application in the medical field. Biosurfactants are also utilized in various fields like the pharmaceuticals, cosmetics, food, and oil industries. However, they have their drawbacks, which include high production costs, variability in production yield, sensitivity to the environment, lack of standardization, hurdles in regulatory approval, and research and development limitations. Despite certain drawbacks, biosurfactant offers a sustainable alternative to synthetic surfactants.
生物表面活性剂:合成表面活性剂的可持续替代品及其应用
生物表面活性剂是由微生物产生的表面活性剂,有助于降低油和水等两种不相溶液体之间的表面张力或界面张力。近年来,由于生物表面活性剂对环境友好,且在各行各业应用广泛,因此可作为合成表面活性剂的可持续替代品。这篇综述文章概述了生物表面活性剂,强调了生物表面活性剂的必要性、生产工艺以及根据分子量、电荷和衍生微生物进行的分类。生物表面活性剂的优点包括生物降解性、生物相容性、低毒性、表面活性和特异性,生物表面活性剂使用的各个领域包括乳化性、热稳定性、pH 稳定性、润湿性、发泡性和铺展性。本综述还重点介绍了在纳米粒子、脂质体、透皮应用、纳米乳液和纳米胶囊等各种配方中使用生物表面活性剂的研究,以支持其在医疗领域的应用。生物表面活性剂还被用于制药、化妆品、食品和石油工业等多个领域。然而,生物表面活性剂也有其缺点,包括生产成本高、产量不稳定、对环境敏感、缺乏标准化、监管审批障碍以及研发限制等。尽管存在一些缺点,但生物表面活性剂为合成表面活性剂提供了一种可持续的替代品。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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