MODIFIABLE AND NON-MODIFIABLE RISK FACTORS FOR TUBERCULOSIS AMONG ADULTS IN INDONESIA: A SYSTEMATIC REVIEW AND META-ANALYSIS

Q4 Medicine

African Journal of Infectious Diseases Pub Date : 2024-03-08 DOI:10.21010/ajidv18i2.3

R. Nindrea, Rika Susanti, P. M. Indika, Benny Alexander Maisa, Muthia Sukma, Linda Rosalina, Astri Widya, Zuhrah Taufiqa, Dede Rahman Agustian, Rahmi Fithria, Nomira Putri, Dianni Arma Wahyu Setia Ningsih, Bella LucintaRillova Arif Lubis, Ainil Mardiah, Maudy Octarini Ezeddin, Nova Linda, Yosa Tamia Marisa, Afriyeni Sri Rahmi, Anggun Permata Sari, Mimin Oktaviana, Flori Puspa Humani, Mochammad Fariz Amsal

{"title":"MODIFIABLE AND NON-MODIFIABLE RISK FACTORS FOR TUBERCULOSIS AMONG ADULTS IN INDONESIA: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"R. Nindrea, Rika Susanti, P. M. Indika, Benny Alexander Maisa, Muthia Sukma, Linda Rosalina, Astri Widya, Zuhrah Taufiqa, Dede Rahman Agustian, Rahmi Fithria, Nomira Putri, Dianni Arma Wahyu Setia Ningsih, Bella LucintaRillova Arif Lubis, Ainil Mardiah, Maudy Octarini Ezeddin, Nova Linda, Yosa Tamia Marisa, Afriyeni Sri Rahmi, Anggun Permata Sari, Mimin Oktaviana, Flori Puspa Humani, Mochammad Fariz Amsal","doi":"10.21010/ajidv18i2.3","DOIUrl":null,"url":null,"abstract":"Background: Controlling tuberculosis (TB) determinant factors in Indonesia is one way TB control in the community. A review is needed to explore risk factors for TB in Indonesia as the key strategies for accelerating the TB preventive program. Aim: The purpose of this review was to determine modifiable and non-modifiable risk factors for TB among adults in Indonesia. Methods: A meta-analysis was undertaken to review current studies related to modifiable and non-modifiable risk factors for TB among adults in Indonesia. A search of PubMed, ProQuest, and Google Scholar for related articles published (January 2000 until December 2023). The Pooled Odds Ratio (POR) from the acquired data was calculated with a 95% CI. The fixed and random effects analysis was performed. The results were presented as forest plots, and Egger's test was used to examine study bias. Review Manager (RevMan) 5.4 and Stata 14.2 were used to process and analyze all of the data. Results: This study results revealed the POR of non-modifiable risk factors (family history of TB) for TB among adults in Indonesia was 6.08 (95% CI 2.99-12.34). Based on modifiable risk factors, it is known household contact has the highest POR (6.01, 2.57-14.04), followed by malnutrition (5.86, 2.50-13.69), inappropriate ventilation (5.57, 1.74–17.86), diabetes mellitus (4.92, 3.04-7.96), smoking behavior (3.24, 2.22-4.72), and low-income level (2.34, 1.42-3.87). Conclusion: Based on significant factors that are related to TB incidence, the results of this review may be valuable to the government in identifying the optimal strategy for TB prevention among adults.","PeriodicalId":39108,"journal":{"name":"African Journal of Infectious Diseases","volume":"21 4","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"African Journal of Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21010/ajidv18i2.3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Controlling tuberculosis (TB) determinant factors in Indonesia is one way TB control in the community. A review is needed to explore risk factors for TB in Indonesia as the key strategies for accelerating the TB preventive program. Aim: The purpose of this review was to determine modifiable and non-modifiable risk factors for TB among adults in Indonesia. Methods: A meta-analysis was undertaken to review current studies related to modifiable and non-modifiable risk factors for TB among adults in Indonesia. A search of PubMed, ProQuest, and Google Scholar for related articles published (January 2000 until December 2023). The Pooled Odds Ratio (POR) from the acquired data was calculated with a 95% CI. The fixed and random effects analysis was performed. The results were presented as forest plots, and Egger's test was used to examine study bias. Review Manager (RevMan) 5.4 and Stata 14.2 were used to process and analyze all of the data. Results: This study results revealed the POR of non-modifiable risk factors (family history of TB) for TB among adults in Indonesia was 6.08 (95% CI 2.99-12.34). Based on modifiable risk factors, it is known household contact has the highest POR (6.01, 2.57-14.04), followed by malnutrition (5.86, 2.50-13.69), inappropriate ventilation (5.57, 1.74–17.86), diabetes mellitus (4.92, 3.04-7.96), smoking behavior (3.24, 2.22-4.72), and low-income level (2.34, 1.42-3.87). Conclusion: Based on significant factors that are related to TB incidence, the results of this review may be valuable to the government in identifying the optimal strategy for TB prevention among adults.

查看原文本刊更多论文

印度尼西亚成人结核病的可改变和不可改变风险因素：系统回顾和荟萃分析

背景：在印度尼西亚，控制结核病（TB）的决定性因素是在社区控制结核病的一种方法。需要对印尼的结核病风险因素进行研究，并将其作为加快结核病预防计划的关键策略。目的：本综述旨在确定印尼成年人患结核病的可改变和不可改变的风险因素。方法我们进行了一项荟萃分析，以回顾与印尼成人结核病可改变和不可改变风险因素相关的现有研究。在 PubMed、ProQuest 和 Google Scholar 上搜索发表于 2000 年 1 月至 2023 年 12 月的相关文章。根据所获得的数据计算出了汇总风险比（POR），并得出了 95% 的 CI。进行了固定效应和随机效应分析。结果以森林图的形式呈现，并使用 Egger 检验来检查研究偏倚。使用综述管理器（RevMan）5.4 和 Stata 14.2 处理和分析所有数据。结果研究结果显示，印尼成人结核病不可改变风险因素（结核病家族史）的POR为6.08（95% CI为2.99-12.34）。在可改变的风险因素中，家庭接触因素的 POR 值最高（6.01，2.57-14.04），其次是营养不良（5.86，2.50-13.69）、通风不当（5.57，1.74-17.86）、糖尿病（4.92，3.04-7.96）、吸烟行为（3.24，2.22-4.72）和低收入水平（2.34，1.42-3.87）。结论基于与肺结核发病率相关的重要因素，本综述的结果可能对政府确定预防成人肺结核的最佳策略很有价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

African Journal of Infectious Diseases Medicine-Infectious Diseases

CiteScore

1.60

自引率

0.00%

发文量