Descriptive Study of Organophosphorus Poisoning in the Post Graduated Hospital Khost Afghanistan

Journal for Research in Applied Sciences and Biotechnology Pub Date : 2024-03-13 DOI:10.55544/jrasb.3.1.41

Azatullah Sajad, Jawid Shah Sarwari, Mohammad Kamil Sabirzai, Sherzad Gul Sharif

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Abstract

Organophosphorus poisoning is an acute intoxication that occurs when certain insecticides (karbofos, chlorophos, thiophos) or chemical warfare agents (sarin, soman, VI gases) enter the body through inhalation, transdermal or oral intake. Poisoning with them accounts for 1-2% of the total number of acute toxicoses. (1) The poison is able to penetrate the skin without damaging it. At high concentrations of the xenobiotic, pathological symptoms appear within a few minutes. Organophosphorus compounds dispersed in the air form a persistent cloud located near the surface of the earth, which persists for 4-6 hours. Military chemical agents are capable of maintaining toxic concentrations for several days. Lethal doses are vary greatly depending on the properties of the particular compound. Methodology: Our study is a descriptive case series conducted in the year 1399 (1st 6 months). Among 1274 inpatients that were admitted in Khost post graduated Hospital during that time, 50 patients were diagnosed with organophosphorus poisoning. Goals of Research: Determining the Frequency and Pattern of Organophosphorus poising in Khost post graduated Hospital during 1399 (1st 6 month) hejri shamsi.

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阿富汗霍斯特毕业后医院有机磷中毒描述性研究

有机磷中毒是指通过吸入、透皮或口服进入人体的某些杀虫剂（杀虫磷、氯磷、硫磷）或化学战剂（沙林毒气、索曼毒气、VI 气体）引起的急性中毒。这些毒剂中毒占急性中毒总数的 1-2%。(1) 毒物能够穿透皮肤而不对皮肤造成损害。异生物浓度高时，病理症状会在几分钟内出现。散布在空气中的有机磷化合物会在地球表面附近形成持久云雾，持续 4-6 个小时。军用化学制剂的毒性浓度可维持数天。致命剂量因特定化合物的特性而有很大差异。研究方法：我们的研究是在 1399 年（前 6 个月）进行的描述性病例系列。在霍斯特毕业后医院收治的 1274 名住院病人中，有 50 名病人被诊断为有机磷中毒。研究目标确定霍斯特毕业后医院在 1399 年（前 6 个月）hejri shamsi 发生有机磷中毒的频率和模式。

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Journal for Research in Applied Sciences and Biotechnology

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