Survival Outcomes in Different Sino-nasal Malignancies: An Institutional Review

Abstract

Objective: The purpose of this review is to comprehend the treatment outcome of different PNS cancer histologies and their survival. Materials and Procedures: A review of our institutional database from January 2010 to December 2022 included 122 sinonasal cancer patients. After exclusions, 84 patients whose data sets were complete underwent analysis. Overall survival (OS), loco-regional failure-free survival (LRFS), and distant metastases-free survival (DMFS) were the measured endpoints. Results: With a median follow-up time of 26 months, there was no correlation detected between histological type and OS, LRFS, or DMFS. It was discovered that the type of treatment technique was substantially related to LRFS. Surgery plus adjuvant radiation and/or chemotherapy had a minor tendency to be significant in terms of OS, with a median OS of 56 months (95% CI: 38.6–73.3). Conclusions: It showed that the use of different treatment modalities had an impact on LRFS, while the type of histology did not correlate with the effectiveness of the treatment.