Synthesis and characterization of chemosensor: Investigation of cyanide sensing and study as live cell imaging

IF 1.3 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Main Group Chemistry Pub Date : 2024-03-15 DOI:10.3233/mgc-240001

Shiva Arun, A. K. Tripathi, Puspendra Singh

引用次数: 0

Abstract

Chemosensor A , (E)-(4-(2-((2-hydroxynaphthalene-1-yl)methylene)hydrazinyl)benzonitrile has been synthesized by condensation of 4-cyanophenylhydrazine hydrochloride with 2-hydroxy-1-naphthaldehyde in ethanol solvent at ∼80°C. The chemosensor A , has been characterized by FT-IR, ESI-MS and 1H-NMR spectroscopic techniques. The chemosensor A has been investigated for selective cyanide ion sensing ability through UV–visible and fluorescence spectra. Further the chemosensor A was also employed as live cell imaging reagent for intra-cellular detection of cyanide ion in SW480 cells.

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化学传感器的合成与表征：氰化物传感调查和活细胞成像研究

化学传感器 A ，(E)-(4-(2-((2-羟基萘-1-基)亚甲基)肼基)苯腈是由 4-氰基苯肼盐酸盐与 2-羟基-1-萘甲醛在乙醇溶剂中于 ∼80°C 缩合合成的。化学传感器 A 已通过 FT-IR、ESI-MS 和 1H-NMR 光谱技术进行了表征。通过紫外可见光谱和荧光光谱研究了化学传感器 A 对氰离子的选择性感应能力。此外，化学传感器 A 还被用作活细胞成像试剂，用于 SW480 细胞中氰离子的细胞内检测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Main Group Chemistry 化学-化学综合

CiteScore

2.00

自引率

26.70%

发文量

审稿时长

>12 weeks

期刊介绍： Main Group Chemistry is intended to be a primary resource for all chemistry, engineering, biological, and materials researchers in both academia and in industry with an interest in the elements from the groups 1, 2, 12–18, lanthanides and actinides. The journal is committed to maintaining a high standard for its publications. This will be ensured by a rigorous peer-review process with most articles being reviewed by at least one editorial board member. Additionally, all manuscripts will be proofread and corrected by a dedicated copy editor located at the University of Kentucky.