Correlation of vitamin A levels in umbilical cord blood with neonatal pulmonary diseases

IF 2.3 4区 医学 Q2 PEDIATRICS
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引用次数: 0

Abstract

Objective

To study the relationship between umbilical cord blood vitamin A (VA) and neonatal lung diseases and explore the impact of umbilical cord blood VA on neonatal lung diseases.

Method

Umbilical vein blood was collected at birth, and its VA content was measured. According to the VA levels in umbilical cord blood, a VA deficiency (VAD) group, a marginal deficiency group and a normal group were created and followed up until 28 days after birth.

Results

The umbilical cord blood VA level in the neonatal group with lung disease was 0.13 ± 0.05 mg/L, while the result for the VA level in the non-lung disease group was 0.15 ± 0.05 mg/L. The umbilical cord blood VA levels in the neonatal lung disease group were significantly lower than those in the non-lung disease group. The incidence of neonatal pulmonary diseases was highest in the VAD group, and the incidence decreased as the level of VA in umbilical cord blood increased. Umbilical cord blood VAD and premature birth were found to be independent risk factors for neonatal respiratory disease.

Conclusion

Umbilical cord blood VAD and premature birth are independent risk factors for neonatal pulmonary diseases. The lower the level of VA in umbilical cord blood, the more susceptible infants will be to neonatal respiratory infections in the neonatal period.

脐带血中维生素 A 水平与新生儿肺部疾病的相关性。
目的研究脐带血维生素 A(VA)与新生儿肺部疾病的关系,探讨脐带血 VA 对新生儿肺部疾病的影响:方法:采集新生儿出生时的脐带血,测定其维生素A含量。根据脐带血中的VA含量,分为VA缺乏(VAD)组、边缘缺乏组和正常组,并随访至出生后28天:结果:新生儿肺部疾病组的脐带血VA水平为0.13 ± 0.05 mg/L,而非肺部疾病组的VA水平为0.15 ± 0.05 mg/L。新生儿肺部疾病组的脐带血 VA 水平明显低于非肺部疾病组。VAD 组新生儿肺部疾病的发病率最高,随着脐带血中 VA 含量的增加,发病率下降。脐带血VAD和早产是新生儿呼吸系统疾病的独立危险因素:结论:脐带血VAD和早产是新生儿肺部疾病的独立危险因素。脐带血中 VA 含量越低,婴儿在新生儿期越容易患新生儿呼吸道感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.10
自引率
0.00%
发文量
170
审稿时长
48 days
期刊介绍: Pediatrics and Neonatology is the official peer-reviewed publication of the Taiwan Pediatric Association and The Society of Neonatology ROC, and is indexed in EMBASE and SCOPUS. Articles on clinical and laboratory research in pediatrics and related fields are eligible for consideration.
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