Evaluation of Features in Probably Benign and Malignant Nonmass Enhancement in Breast MRI.

IF 1.6 Q4 ONCOLOGY
International Journal of Breast Cancer Pub Date : 2024-03-15 eCollection Date: 2024-01-01 DOI:10.1155/2024/6661849
Nasrin Ahmadinejad, Fahimeh Azizinik, Pershang Khosravi, Ala Torabi, Amirhassan Mohajeri, Arvin Arian
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引用次数: 0

Abstract

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a highly sensitive breast imaging modality in detecting breast carcinoma. Nonmass enhancement (NME) is uniquely seen on MRI of the breast. The correlation between NME features and pathologic results has not been extensively explored. Our goal was to evaluate the characteristics of probably benign and suspicious NME lesions in MRI and determine which features are more associated with malignancy. We performed a retrospective research after approval by the hospital ethics committee on women who underwent breast MRI from March 2017 to March 2020 and identified 63 lesions of all 400 NME that were categorized as probably benign or suspicious according to the BI-RADS classification (version 2013). MRI features of NME findings including the location, size, distribution and enhancement pattern, kinetic curve, diffusion restriction, and also pathology result or 6-12-month follow-up MRI were evaluated and analyzed in each group (probably benign or suspicious NME). Vacuum-guided biopsies (VAB) were performed under mammographic or sonographic guidance and confirmed with MRI by visualization of the inserted clips. Segmental distribution and clustered ring internal enhancement were significantly associated with malignancy (p value<0.05), while linear distribution or homogeneous enhancement patterns were associated with benignity (p value <0.05). Additionally, the plateau and washout types in the dynamic curve were only seen in malignant lesions (p value <0.05). The presence of DWI restriction in NME lesions was also found to be a statistically important factor. Understanding the imaging findings of malignant NME is helpful to determine when biopsy is indicated. The correlation between NME features and pathologic results is critical in making appropriate management.

评估乳腺 MRI 中可能存在的良性和恶性非肿块增强的特征。
动态对比增强磁共振成像(DCE-MRI)是一种高灵敏度的乳腺成像模式,可用于检测乳腺癌。非肿块增强(NME)是乳腺磁共振成像的独特表现。NME 特征与病理结果之间的相关性尚未得到广泛探讨。我们的目标是评估核磁共振成像中可能是良性和可疑的 NME 病变的特征,并确定哪些特征与恶性肿瘤更相关。经医院伦理委员会批准后,我们对 2017 年 3 月至 2020 年 3 月期间接受乳腺 MRI 检查的女性进行了回顾性研究,在所有 400 个 NME 病灶中确定了 63 个病灶,并根据 BI-RADS 分类(2013 版)将其归类为可能良性或可疑病灶。对每组(可能是良性或可疑的 NME)NME 发现的 MRI 特征进行了评估和分析,包括位置、大小、分布和增强模式、动力学曲线、弥散受限以及病理结果或 6-12 个月的随访 MRI。真空引导活检(VAB)是在乳腺X光或超声引导下进行的,并通过核磁共振成像确认插入的夹子。节段性分布和簇状环形内部强化与恶性程度显著相关(P值P值
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来源期刊
CiteScore
3.40
自引率
0.00%
发文量
25
审稿时长
19 weeks
期刊介绍: International Journal of Breast Cancer is a peer-reviewed, Open Access journal that provides a forum for scientists, clinicians, and health care professionals working in breast cancer research and management. The journal publishes original research articles, review articles, and clinical studies related to molecular pathology, genomics, genetic predisposition, screening and diagnosis, disease markers, drug sensitivity and resistance, as well as novel therapies, with a specific focus on molecular targeted agents and immune therapies.
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