WITHDRAWN: Comparison of the Efficacy of Oral Magnesium with Oral Ketorolac for Postoperative Pain Management in Anorectal Surgery: A Double-blinded Randomized Clinical Trial

IF 1.4 Q4 PHARMACOLOGY & PHARMACY

Reviews on recent clinical trials Pub Date : 2024-03-21 DOI:10.2174/0115748871290318240218195517

Seyed Jalal Eshagh Hoseini, Farzanesadat Ghazi, Mohsen Eshraghi, Mostafa Vahedian, Mohammad Reza Pashaei, Mohamad Amin Habibi, Sajjad Ahmadpour

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引用次数: 0

Abstract

The article has been withdrawn at the request of the editor of the journal Reviews on Recent Clinical Trials.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php

Bentham science disclaimer: It is a condition of publication that manuscripts submitted to this journal have not been published and will not be simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyright of their article is transferred to the publishers if and when the article is accepted for publication.

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口服镁与口服酮咯酸治疗肛门直肠手术术后疼痛的疗效比较：双盲随机临床试验。

背景：由于肛门直肠手术患者术后会出现疼痛，而且疼痛会影响患者的生活质量，因此我们旨在比较口服镁剂和口服酮咯酸的镇痛效果，以便为这些患者选择合适的镇痛药物：本研究是一项双盲、随机临床试验，对象是 104 名接受肛门直肠手术的患者。患者被随机分为两组。第一组接受口服镁（每天 250 毫克），第二组接受口服酮咯酸（每天 10 毫克）。患者在手术后 2 小时服药，并在 10 天内每 12 小时服药一次。根据视觉模拟量表和数字评分量表记录术后每 24 小时的疼痛测量结果：研究发现，服用镁片的患者术后疼痛减轻的情况与酮咯酸组相似。在服用酮咯酸的组别中也观察到了类似的减轻趋势；然而，镁片组的减轻趋势更为明显，并且在第 1、3 和 5 天具有显著的统计学意义（P < 0.001）。然而，在术后第七天（p = 0.093）和第十天（p = 0.088），两组之间的差异并不显著：结论：术后服用镁片具有适当的镇痛效果，从第五天开始，其镇痛效果与口服酮咯酸片相似，但在最初几天，据统计其镇痛效果不如酮咯酸片。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Reviews on recent clinical trials PHARMACOLOGY & PHARMACY-

CiteScore

3.10

自引率

5.30%

发文量

期刊介绍： Reviews on Recent Clinical Trials publishes frontier reviews on recent clinical trials of major importance. The journal"s aim is to publish the highest quality review articles in the field. Topics covered include: important Phase I – IV clinical trial studies, clinical investigations at all stages of development and therapeutics. The journal is essential reading for all researchers and clinicians involved in drug therapy and clinical trials.