Evaluating the effect of long-term exposure to ozone on lung function by different metrics

IF 2.9 4区环境科学与生态学 Q3 ENVIRONMENTAL SCIENCES

Air Quality Atmosphere and Health Pub Date : 2024-03-23 DOI:10.1007/s11869-024-01546-x

Carmel Raz-Maman, Nili Borochov-Greenberg, Rafael Y. Lefkowitz, Boris A. Portnov

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Abstract

Background

The majority of studies examining long-term exposure to ambient ozone have utilized averages as the exposure parameter. However, averaging ozone exposures may underestimate the impact of ozone peaks and seasonality. The current study aimed to examine the association between ozone exposure evaluated by different exposure metrics and lung function in healthy adolescents.

Methods

We conducted a cross-sectional study among 665 healthy adolescent males living within a 2 km radius of an ozone monitoring station. Multiple ozone exposure metrics were evaluated, including two-year and peak-season averages, peaks, peak intensity, and the total excess of peak level. Lung function was measured using FEV₁, FVC, and FEV₁/FVC ratio.

Results

The peak intensity during the ozone peak-season was associated with the largest decrease in the FEV₁/FVC ratio, -1.52% (95%CI: -2.55%, -0.49%) (p < 0.01). Concurrently, we did not observe a significant association between ozone exposure, assessed by different metrics, and either FEV₁ or FVC.

Conclusions

The study findings suggest that when evaluating ambient ozone exposures, ozone peak intensity during peak-season should be considered, as it may predict greater adverse health effects than averages alone.

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通过不同指标评估长期暴露于臭氧对肺功能的影响

背景大多数研究在研究长期暴露于环境臭氧时，都使用平均值作为暴露参数。然而，臭氧暴露的平均值可能会低估臭氧峰值和季节性的影响。本研究旨在探讨通过不同暴露指标评估的臭氧暴露量与健康青少年肺功能之间的关系。方法我们对居住在臭氧监测站 2 公里半径范围内的 665 名健康青少年男性进行了横断面研究。我们对多种臭氧暴露指标进行了评估，包括两年和高峰季节的平均值、峰值、峰值强度和峰值水平的总过量。结果臭氧高峰季节的峰值强度与 FEV1/FVC 比率的最大降幅-1.52%（95%CI：-2.55%, -0.49%）相关（p <0.01）。结论：研究结果表明，在评估环境臭氧暴露时，应考虑到旺季的臭氧峰值强度，因为它可能比单纯的平均值更能预测对健康的不利影响。

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来源期刊

Air Quality Atmosphere and Health ENVIRONMENTAL SCIENCES-

CiteScore

8.80

自引率

2.00%

发文量

146

审稿时长

>12 weeks

期刊介绍： Air Quality, Atmosphere, and Health is a multidisciplinary journal which, by its very name, illustrates the broad range of work it publishes and which focuses on atmospheric consequences of human activities and their implications for human and ecological health. It offers research papers, critical literature reviews and commentaries, as well as special issues devoted to topical subjects or themes. International in scope, the journal presents papers that inform and stimulate a global readership, as the topic addressed are global in their import. Consequently, we do not encourage submission of papers involving local data that relate to local problems. Unless they demonstrate wide applicability, these are better submitted to national or regional journals. Air Quality, Atmosphere & Health addresses such topics as acid precipitation; airborne particulate matter; air quality monitoring and management; exposure assessment; risk assessment; indoor air quality; atmospheric chemistry; atmospheric modeling and prediction; air pollution climatology; climate change and air quality; air pollution measurement; atmospheric impact assessment; forest-fire emissions; atmospheric science; greenhouse gases; health and ecological effects; clean air technology; regional and global change and satellite measurements. This journal benefits a diverse audience of researchers, public health officials and policy makers addressing problems that call for solutions based in evidence from atmospheric and exposure assessment scientists, epidemiologists, and risk assessors. Publication in the journal affords the opportunity to reach beyond defined disciplinary niches to this broader readership.