New migraine drugs: A critical appraisal of the reason why the majority of migraine patients do not receive an adequate medication.

IF 5 2区 医学 Q1 CLINICAL NEUROLOGY
Hans Christoph Diener, Arne May
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引用次数: 0

Abstract

The last three decades have produced several novel and efficient medications to treat migraine attacks and reduce attack frequency. Additionally, promising approaches for the development of acute therapy and migraine prophylaxis continue to be pursued. At the same time as we witness the development of better and more efficient medications with continuously fewer side effects, we also realise that the high cost of such therapies means that only a minority of migraine patients who could benefit from these medications can afford them. Furthermore, information on cost-effectiveness is still lacking. Here, we compare availiable data, highlight open questions and suggest trials to close knowledge gaps. With good reason, our medicine is evidence-based. However, if this evidence is not collected, our decisions will continue to be based on marketing and assumptions. At the moment, we are not doing justice to our patients.

偏头痛新药:对大多数偏头痛患者得不到适当药物治疗的原因进行批判性评估。
在过去的三十年中,已经有多种新型高效药物用于治疗偏头痛发作并降低发作频率。此外,开发急性疗法和偏头痛预防方法的工作也在继续进行。在我们见证更好、更有效、副作用更少的药物不断发展的同时,我们也意识到,这些疗法的高昂费用意味着只有少数能够从这些药物中获益的偏头痛患者能够负担得起。此外,有关成本效益的信息仍然缺乏。在此,我们将对现有数据进行比较,强调尚未解决的问题,并建议进行试验以填补知识空白。我们的医学以证据为基础,这是有充分理由的。但是,如果不收集这些证据,我们的决策将继续以营销和假设为基础。此时此刻,我们对病人并不公平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cephalalgia
Cephalalgia 医学-临床神经学
CiteScore
10.10
自引率
6.10%
发文量
108
审稿时长
4-8 weeks
期刊介绍: Cephalalgia contains original peer reviewed papers on all aspects of headache. The journal provides an international forum for original research papers, review articles and short communications. Published monthly on behalf of the International Headache Society, Cephalalgia''s rapid review averages 5 ½ weeks from author submission to first decision.
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