The management of patients with inflammatory bowel disease-associated spondyloarthritis: Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD) and Italian Society of Rheumatology (SIR) recommendations based on a pseudo-Delphi consensus

IF 9.2 1区 医学 Q1 IMMUNOLOGY
Fabio Salvatore Macaluso , Flavio Caprioli , Laura Benedan , Cristina Bezzio , Roberto Caporali , Alberto Cauli , Maria Sole Chimenti , Francesco Ciccia , Salvatore D'Angelo , Massimo Claudio Fantini , Stefano Festa , Florenzo Iannone , Ennio Lubrano , Paolo Mariani , Claudio Papi , Giuseppe Provenzano , Daniela Pugliese , Antonio Rispo , Simone Saibeni , Carlo Salvarani , Roberto Gerli
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引用次数: 0

Abstract

Spondyloarthritis (SpA) is the most frequent extraintestinal manifestation in patients with inflammatory bowel diseases (IBD). When IBD and spondyloarthritis coexist, musculoskeletal and intestinal disease features should be considered when planning a therapeutic strategy. Treatment options for IBD and SpA have expanded enormously over the last few years, but randomized controlled trials with specific endpoints focused on SpA are not available in the IBD setting. To address this important clinical topic, the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD) and the Italian Society of Rheumatology (SIR) jointly planned to draw updated therapeutic recommendations for IBD-associated SpA using a pseudo-Delphi method. This document presents the official recommendations of IG-IBD and SIR on the management of IBD-associated SpA in the form of 34 statements and 4 therapeutic algorithms. It is intended to be a reference guide for gastroenterologists and rheumatologists dealing with IBD-associated SpA.

炎症性肠病相关脊柱关节炎患者的治疗:意大利炎症性肠病研究小组(IG-IBD)和意大利风湿病学会(SIR)根据伪德尔菲共识提出的建议。
脊柱关节炎(Spondyloarthritis,SPA)是炎症性肠病(IBD)患者最常见的肠外表现。当 IBD 和脊柱关节炎同时存在时,在制定治疗策略时应考虑肌肉骨骼和肠道疾病的特征。在过去几年中,IBD 和脊柱关节炎的治疗方案有了很大的扩展,但在 IBD 环境中,还没有针对脊柱关节炎的特定终点的随机对照试验。为了解决这一重要的临床课题,意大利炎症性肠病研究小组(IG-IBD)和意大利风湿病学会(SIR)共同计划采用伪德尔菲法,为 IBD 相关性 SpA 制定最新的治疗建议。本文件以 34 项声明和 4 种治疗算法的形式,介绍了 IG-IBD 和 SIR 对 IBD 相关性 SpA 治疗的官方建议。它旨在为消化内科医生和风湿病学家处理 IBD 相关性 SpA 提供参考指南。
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来源期刊
Autoimmunity reviews
Autoimmunity reviews 医学-免疫学
CiteScore
24.70
自引率
4.40%
发文量
164
审稿时长
21 days
期刊介绍: Autoimmunity Reviews is a publication that features up-to-date, structured reviews on various topics in the field of autoimmunity. These reviews are written by renowned experts and include demonstrative illustrations and tables. Each article will have a clear "take-home" message for readers. The selection of articles is primarily done by the Editors-in-Chief, based on recommendations from the international Editorial Board. The topics covered in the articles span all areas of autoimmunology, aiming to bridge the gap between basic and clinical sciences. In terms of content, the contributions in basic sciences delve into the pathophysiology and mechanisms of autoimmune disorders, as well as genomics and proteomics. On the other hand, clinical contributions focus on diseases related to autoimmunity, novel therapies, and clinical associations. Autoimmunity Reviews is internationally recognized, and its articles are indexed and abstracted in prestigious databases such as PubMed/Medline, Science Citation Index Expanded, Biosciences Information Services, and Chemical Abstracts.
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