Risk Factors of Enternal Nutrition Intolerance in Septic Patients: A Case-control Study.

IF 2 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Current Medical Science Pub Date : 2024-04-01 Epub Date: 2024-03-22 DOI:10.1007/s11596-024-2849-3

Li-Zhu Wang, Yan Xiang, Qian Li, Yi-Rong Zhu, Jue Fang, Xiao-Dan Lu, Zhao-Cai Zhang

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引用次数: 0

Abstract

Objective: This study aimed to investigate the incidence of enteral nutrition intolerance (ENI) in patients with sepsis and explore potential risk factors.

Methods: A case-control study was conducted in patients with sepsis who were receiving enteral nutrition (EN) at a tertiary hospital in China. The included patients were divided into the ENI group and the non-ENI group. Univariate and multivariate analyses were performed to identify the risk factors for ENI.

Results: A total of 859 patients were included in the study. Among them, 288 (33.53%) patients experienced symptoms of ENI, including diarrhea, vomiting, bloating, and gastric retention. Logistic regression analysis revealed that the Acute Physiology and Chronic Health Evaluation H (APACHE H) score, thoracocentesis, and usage of cardiotonic drugs (namely, inotropes) were independent predictors of the ENI.

Conclusion: The incidence of ENI is relatively high in patients with sepsis, especially in those who have higher APACHE H scores, have undergone thoracocentesis, and have received inotropes.

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败血症患者肠内营养不耐受的风险因素：病例对照研究

研究目的本研究旨在调查脓毒症患者肠内营养不耐受（ENI）的发生率，并探讨潜在的风险因素：方法：在中国一家三级医院对接受肠内营养（EN）的败血症患者进行病例对照研究。纳入的患者被分为ENI组和非ENI组。通过单变量和多变量分析确定ENI的风险因素：研究共纳入 859 例患者。其中，288 例（33.53%）患者出现 ENI 症状，包括腹泻、呕吐、腹胀和胃潴留。逻辑回归分析显示，急性生理学和慢性健康评估 H（APACHE H）评分、胸腔穿刺术和使用强心药物（即肌注）是预测 ENI 的独立因素：结论：脓毒症患者ENI的发生率相对较高，尤其是APACHE H评分较高、接受过胸腔穿刺术和使用过肌注药物的患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Medical Science Biochemistry, Genetics and Molecular Biology-Genetics

CiteScore

4.70

自引率

0.00%

发文量

126

期刊介绍： Current Medical Science provides a forum for peer-reviewed papers in the medical sciences, to promote academic exchange between Chinese researchers and doctors and their foreign counterparts. The journal covers the subjects of biomedicine such as physiology, biochemistry, molecular biology, pharmacology, pathology and pathophysiology, etc., and clinical research, such as surgery, internal medicine, obstetrics and gynecology, pediatrics and otorhinolaryngology etc. The articles appearing in Current Medical Science are mainly in English, with a very small number of its papers in German, to pay tribute to its German founder. This journal is the only medical periodical in Western languages sponsored by an educational institution located in the central part of China.