Acute lymphoblastic leukemia with pseudo-Chediak-Higashi granules in the initial diagnosis and relapse

IF 2.2 4区医学 Q3 HEMATOLOGY

International Journal of Laboratory Hematology Pub Date : 2024-03-22 DOI:10.1111/ijlh.14271

Rongjie Li, Shimei Xia, Yingyan Liao, Bailing Zhou

引用次数: 0

Abstract

Pseudo-Chediak-Higashi granules are large cytoplasmic inclusions commonly encountered in myeloblasts or other myeloid precursors in acute myeloid leukemia and myelodysplastic syndromes. However, pseudo-Chediak-Higashi granules are rarely found in acute lymphoblastic leukemia (ALL). We present the case of an 8-year-old boy who was diagnosed with ALL with pseudo-Chediak-Higashi granules in the initial diagnosis and relapse, acting like a characteristic marker.

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急性淋巴细胞白血病初诊和复发时伴有假性切迪克-希加希颗粒。

假性切迪克-希氏颗粒是急性髓性白血病和骨髓增生异常综合征中髓母细胞或其他髓系前体常见的大细胞质内含物。然而，在急性淋巴细胞白血病（ALL）中很少发现假性切迪克-希氏颗粒。我们介绍了一例被诊断为ALL的8岁男孩的病例，他在初诊和复发时都出现了假性切迪克-希格希颗粒，这就像一个特征性标记物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Laboratory Hematology 医学-血液学

CiteScore

4.50

自引率

6.70%

发文量

211

审稿时长

6-12 weeks

期刊介绍： The International Journal of Laboratory Hematology provides a forum for the communication of new developments, research topics and the practice of laboratory haematology. The journal publishes invited reviews, full length original articles, and correspondence. The International Journal of Laboratory Hematology is the official journal of the International Society for Laboratory Hematology, which addresses the following sub-disciplines: cellular analysis, flow cytometry, haemostasis and thrombosis, molecular diagnostics, haematology informatics, haemoglobinopathies, point of care testing, standards and guidelines. The journal was launched in 2006 as the successor to Clinical and Laboratory Hematology, which was first published in 1979. An active and positive editorial policy ensures that work of a high scientific standard is reported, in order to bridge the gap between practical and academic aspects of laboratory haematology.