Metabolic syndrome burden, determinants and treatment status in an urban slum resettlement colony in Delhi, India.

IF 2.3 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Shivani Rao, Saurav Basu, Kajal Nandi, M M Singh, Heena Lalwani, Vansh Maheshwari, Amod Borle, Nandini Sharma
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引用次数: 0

Abstract

Background: Metabolic syndrome (MetS) in low-resource settings contributes to accentuated risk of cardiovascular disease, including stroke. The study objective was to estimate the prevalence, determinants and treatment status of MetS in an urban slum resettlement population in Delhi, India.

Methods: This study was conducted from February to May 2023. Multiphase sampling was conducted with 1910 individuals screened for abdominal obesity (AO), with 996 detected as having AO, of which, 400 were selected by simple random sampling and further evaluated for triglycerides (TGs), high-density lipoprotein (HDL) and fasting glucose levels.

Results: Among the 400 participants detected as having AO, 211 had evidence of MetS (52.75% [95% confidence interval 47.83 to 57.62]). The most prevalent combination of MetS clustering was for all five components (AO, diabetes mellitus [DM], hypertension [HTN], low HDL and high TGs; 14.69%), followed by AO, DM and HTN (12.32%). On adjusted analysis, the odds of having MetS was found to be independently associated with increasing age (≥40 y) but not sex.

Conclusions: A high burden of MetS and suboptimal treatment status is prevalent in urban slum populations. Screening of individuals with AO, especially in those >40 y of age, can be an effective programmatic strategy for early diagnosis and management of MetS and its underlying components.

印度德里一个城市贫民窟安置区的代谢综合征负担、决定因素和治疗状况。
背景:在资源匮乏的环境中,代谢综合征(MetS)会增加心血管疾病(包括中风)的风险。本研究旨在估算印度德里城市贫民窟安置人口中代谢综合征的患病率、决定因素和治疗状况:本研究于 2023 年 2 月至 5 月进行。方法:这项研究于 2023 年 2 月至 5 月进行,对 1910 人进行了腹部肥胖(AO)筛查,其中 996 人被检测出患有腹部肥胖症,通过简单随机抽样选取了其中 400 人,并对其甘油三酯(TGs)、高密度脂蛋白(HDL)和空腹血糖水平进行了进一步评估:在被检测出患有 AO 的 400 名参与者中,211 人有 MetS 的证据(52.75% [95% 置信区间 47.83 至 57.62])。最常见的 MetS 组合是所有五个组成部分(AO、糖尿病[DM]、高血压[HTN]、低 HDL 和高 TGs;14.69%),其次是 AO、DM 和高血压(12.32%)。经调整分析发现,患有 MetS 的几率与年龄的增加(≥40 岁)独立相关,但与性别无关:结论:在城市贫民窟人群中普遍存在着高代谢性疾病负担和治疗效果不理想的情况。对AO患者,尤其是年龄大于40岁的患者进行筛查,是早期诊断和管理MetS及其潜在因素的有效方案策略。
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来源期刊
International Health
International Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
4.50
自引率
0.00%
发文量
83
审稿时长
>12 weeks
期刊介绍: International Health is an official journal of the Royal Society of Tropical Medicine and Hygiene. It publishes original, peer-reviewed articles and reviews on all aspects of global health including the social and economic aspects of communicable and non-communicable diseases, health systems research, policy and implementation, and the evaluation of disease control programmes and healthcare delivery solutions. It aims to stimulate scientific and policy debate and provide a forum for analysis and opinion sharing for individuals and organisations engaged in all areas of global health.
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