Outcomes of open reduction and internal fixation of calcaneus fractures: A database study comparing patients with and without diabetes.

IF 3.8 3区 医学 Q2 CELL BIOLOGY
Wound Repair and Regeneration Pub Date : 2024-07-01 Epub Date: 2024-03-22 DOI:10.1111/wrr.13169
Matthew J Johnson, Benjamin M Conover, Robert G Frykberg, Katherine M Raspovic, Lawrence A Lavery, Dane K Wukich
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Abstract

Treatment of calcaneal fractures in patients with diabetes mellitus (DM) is challenging. The purpose of this study was to compare post-operative outcomes after open reduction and internal fixation (ORIF) for calcaneus fracture in patients with complicated DM, uncomplicated DM, and patients without DM. A commercially available de-identified database was queried for all calcaneus fracture diagnoses undergoing ORIF from 2010 to 2021. The patients were separated into three groups for analysis: patients without DM (10,951, 82.6%), uncomplicated DM (1,500, 11.3%) and complicated DM (802, 6.1%). At 1 year, post-operative adverse events were assessed among the three groups. The odds of adverse event(s) for each group were compared between the three groups with and without characteristic matching. In the unmatched cohorts, patients with complicated DM, when compared with patients without DM and patients with uncomplicated DM, had significantly higher rates of all adverse events with exception of DVT. Rates of CNA were significantly higher in patients with complicated DM compared with no DM (OR 107.7 (CI 24.83-467.6) p < 0.0001) and uncomplicated DM (OR 44.26 (CI 3.86-507.93) p = 0.0002). After matching, non-union, AKI, sepsis, surgical site infection, and wound disruption were higher in patients with complicated DM compared with patients without DM. There were no significant differences in the three groups with regard to reoperation, DVT, MI, pneumonia, or below the knee amputation. Patients with DM who underwent ORIF for calcaneus fracture experienced higher rates of post-operative adverse events compared with those patients without DM.

方骨骨折切开复位内固定术的疗效:对比糖尿病患者和非糖尿病患者的数据库研究。
糖尿病(DM)患者小腿骨骨折的治疗具有挑战性。本研究旨在比较复杂DM患者、非复杂DM患者和无DM患者小关节骨折切开复位内固定术(ORIF)的术后效果。研究人员查询了 2010 年至 2021 年期间所有接受开放复位内固定术(ORIF)的方骨干骨折诊断患者的商业数据库。这些患者被分为三组进行分析:无DM患者(10951人,占82.6%)、无并发症DM患者(1500人,占11.3%)和并发症DM患者(802人,占6.1%)。一年后,对三组患者的术后不良事件进行了评估。比较了三组患者在特征匹配和未匹配情况下发生不良事件的几率。在未进行特征匹配的组别中,复杂性糖尿病患者与非复杂性糖尿病患者和非复杂性糖尿病患者相比,除深静脉血栓外,所有不良事件的发生率都明显较高。并发症 DM 患者的 CNA 发生率明显高于非并发症 DM 患者(OR 107.7 (CI 24.83-467.6) p
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来源期刊
Wound Repair and Regeneration
Wound Repair and Regeneration 医学-皮肤病学
CiteScore
5.90
自引率
3.40%
发文量
71
审稿时长
6-12 weeks
期刊介绍: Wound Repair and Regeneration provides extensive international coverage of cellular and molecular biology, connective tissue, and biological mediator studies in the field of tissue repair and regeneration and serves a diverse audience of surgeons, plastic surgeons, dermatologists, biochemists, cell biologists, and others. Wound Repair and Regeneration is the official journal of The Wound Healing Society, The European Tissue Repair Society, The Japanese Society for Wound Healing, and The Australian Wound Management Association.
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