When to lavage in the absence of a sonographically visible joint effusion in painful total knee arthroplasty: a retrospective longitudinal study.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-03-22 DOI:10.1007/s00256-024-04657-9
Bashiar Thejeel, Zachary Coles, Qian Li, Joesph T Nguyen, Alberto V Carli, Theodore T Miller
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引用次数: 0

Abstract

Objective: To determine if knee arthroplasty without sonographically visible effusion needs to undergo lavage to rule out infection.

Methods: Patients were accrued by a retrospective search of a longitudinally maintained radiology database looking for patients referred for ultrasound guided aspiration of suspected TKA infection. Clinical presentations, laboratory tests, intraoperative findings, and follow-up were reviewed.

Results: Four hundred sixty-nine patients were included (mean age of 67 years (range, 36-91)) including 251 females. Four hundred three patients had effusions, of which 57 were infected based on ultrasound-guided and surgical aspirates. Sixty-four patients lacked effusions, of which 47 underwent lavage at the clinicians' request, with 6/47 infected. Nineteen patients without effusion were not lavaged at the clinicians' request due to low suspicion, and none were infected. Patients with positive lavage cultures all had clinical risk factors. Infection rates were significantly higher in patients with joint effusion and clinical suspicion for infection compared to absent joint effusion and absent clinical suspicion. A significantly higher proportion of patients with hyperemia or moderate-severe synovial thickening on ultrasound were symptomatic and had joint effusion and positive joint cultures. Aspiration of native fluid had 85% sensitivity and 100% specificity while lavage had a sensitivity of 57% and specificity of 100%. Negative predictive value for native aspirates was 94% compared to 86% for lavage.

Conclusion: A TKA with low clinical suspicion of infection does not need to undergo lavage in the absence of a sonographically visible effusion.

Abstract Image

疼痛性全膝关节置换术中,在声像图未显示关节积液的情况下何时进行灌洗:一项回顾性纵向研究。
目的确定无声像图可见渗出的膝关节置换术是否需要进行灌洗以排除感染:方法:通过回顾性检索纵向维护的放射学数据库,寻找因疑似 TKA 感染而在超声引导下抽液的转诊患者。对患者的临床表现、实验室检查、术中发现和随访情况进行了回顾:共纳入 469 名患者(平均年龄 67 岁(36-91 岁)),包括 251 名女性。443 名患者有积液,根据超声引导和手术抽吸的结果,其中 57 人受到感染。64名患者没有积液,其中47名患者应临床医生的要求接受了灌洗,其中6/47受到感染。19名没有渗出液的患者因怀疑度较低而没有应临床医生的要求进行灌洗,其中没有一人受到感染。灌洗培养呈阳性的患者均有临床风险因素。有关节积液且临床怀疑感染的患者感染率明显高于无关节积液且临床怀疑感染的患者。在超声检查发现有充血或中重度滑膜增厚的患者中,有症状、关节积液和关节培养阳性的比例明显更高。抽吸原液的敏感性为 85%,特异性为 100%,而灌洗的敏感性为 57%,特异性为 100%。原液抽吸的阴性预测值为 94%,而灌洗的阴性预测值为 86%:结论:临床怀疑感染率较低的 TKA 患者在没有声像图可见渗出物的情况下无需进行灌洗。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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