Human papillomavirus vaccination uptake and determinant factors among adolescent schoolgirls in sub-Saharan Africa: A systematic review and meta-analysis.

IF 4.1 4区医学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Human Vaccines & Immunotherapeutics Pub Date : 2024-12-31 Epub Date: 2024-03-20 DOI:10.1080/21645515.2024.2326295

Yordanos Sisay Asgedom, Tsegaye Melaku Kebede, Beminate Lemma Seifu, Kusse Urmale Mare, Zufan Alamrie Asmare, Hiwot Altaye Asebe, Bizunesh Fantahun Kase, Abdu Hailu Shibeshi, Tsion Mulat Tebeje, Kebede Gemeda Sabo, Bezawit Melak Fente, Afework Alemu Lombebo, Mengistu Meskele Koyira, Gizachew Ambaw Kassie

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引用次数: 0

Abstract

Despite the ongoing global vaccination campaign aimed at preventing human papillomavirus (HPV) related health issues, the uptake of the HPV vaccine remains unacceptably low in developing regions, particularly in sub-Saharan Africa (SSA). Therefore, this systematic review and meta-analysis aimed at determining the pooled prevalence and associated factors of HPV vaccine uptake among adolescent school girls in SSA. Electronic bio-medical databases were explored. Pooled prevalence, publication bias, meta-regression, sub-group, and sensitivity analysis were performed. The estimated pooled prevalence of HPV vaccine uptake was 28.53% [95% CI: (5.25, 51.81)]. Having good knowledge and a positive attitude was significantly associated with HPV vaccine uptake in SSA. Subgroup analysis revealed the highest uptake was 62.52% from Kenya and the lowest was 3.77% in Nigeria. The HPV vaccine uptake is low. It underscores the need for community education, school-based immunization, and education programs that promote the uptake of the vaccine to increase coverage.

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撒哈拉以南非洲女学生接种人类乳头瘤病毒疫苗的情况及其决定因素：系统回顾和荟萃分析。

尽管全球正在开展旨在预防人类乳头瘤病毒（HPV）相关健康问题的疫苗接种活动，但在发展中地区，尤其是撒哈拉以南非洲地区（SSA），HPV 疫苗的接种率仍然低得令人无法接受。因此，本系统综述和荟萃分析旨在确定撒哈拉以南非洲地区少女接种 HPV 疫苗的总体流行率和相关因素。研究人员查阅了电子生物医学数据库。对总体流行率、发表偏差、元回归、亚组和敏感性进行了分析。据估计，HPV 疫苗接种率为 28.53% [95% CI：(5.25, 51.81)]。在 SSA，良好的知识和积极的态度与 HPV 疫苗的接种率密切相关。分组分析显示，肯尼亚的接种率最高，为 62.52%，尼日利亚最低，为 3.77%。HPV疫苗的接种率很低。这凸显了社区教育、学校免疫接种和教育计划的必要性，这些计划能促进疫苗的接种，从而提高疫苗的覆盖率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Human Vaccines & Immunotherapeutics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-IMMUNOLOGY

CiteScore

7.90

自引率

8.30%

发文量

489

审稿时长

3-6 weeks

期刊介绍： (formerly Human Vaccines; issn 1554-8619) Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics. Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.