The epidemiological characteristics of sleep disordered breathing in congestive heart failure: A prospective, single centre study in Southeast Asia.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-03-01 Epub Date: 2024-03-20 DOI:10.1177/14782715241239704

Albert Iruthiaraj Lourdesamy Anthony, Rosilawati Abdul Rani

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引用次数: 0

Abstract

Background: The presence of sleep-disordered breathing (SDB) in congestive heart failure (CHF) is associated with poor prognosis and is underdiagnosed despite advances in CHF management. The prevalence of SDB in CHF remains understudied in South East Asia.

Methods: A prospective, observational single-centre study was conducted where 116 consecutive patients in a specialised heart failure clinic underwent level 1, attended polysomnography (PSG).

Results: The prevalence of SDB was 78% using the apnoea-hypopnea index (AHI), AHI ⩾ 5/h threshold, and 59% with the AHI ⩾ 15/h threshold. Obstructive sleep apnoea (OSA) was the predominant type of SDB and was associated with increased body mass index and neck circumference. STOP-BANG was predictive of SDB, especially in men. Central sleep apnoea (CSA) patients had worse sleep indexes and lower awake arterial carbon dioxide. SDB was also homogenously present in preserved ejection fraction (EF) CHF.

Conclusion: Most of the CHF patients were found to have SDB with the utility of PSG. Local CHF guidelines should include sleep testing for all patients with CHF.The study is registered on ClinicalTrials.gov (NCT05332223) as 'The Epidemiological Characteristics of SDB in Patients with Reduced or Preserved EF CHF'.

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充血性心力衰竭患者睡眠呼吸紊乱的流行病学特征：东南亚单中心前瞻性研究。

背景：充血性心力衰竭（CHF）患者出现睡眠呼吸障碍（SDB）与预后不良有关，尽管 CHF 治疗取得了进展，但睡眠呼吸障碍的诊断率却很低。东南亚地区对充血性心力衰竭患者睡眠呼吸障碍患病率的研究仍然不足：方法：进行了一项前瞻性、观察性单中心研究，对心衰专科门诊的 116 名连续患者进行了 1 级多导睡眠图（PSG）检查：采用呼吸暂停-低通气指数（AHI）、AHI ⩾5/h阈值时，SDB的患病率为78%；采用AHI ⩾15/h阈值时，SDB的患病率为59%。阻塞性睡眠呼吸暂停（OSA）是 SDB 的主要类型，与体重指数和颈围的增加有关。STOP-BANG可预测SDB，尤其是男性。中枢性睡眠呼吸暂停（CSA）患者的睡眠指数较差，清醒时动脉二氧化碳含量较低。在射血分数（EF）保留的慢性阻塞性肺疾病患者中，SDB也同样存在：结论：大多数慢性阻塞性肺病患者在进行 PSG 检查时都发现了 SDB。该研究已在 ClinicalTrials.gov (NCT05332223) 上注册，名为 "射血分数降低或保留射血分数的 CHF 患者 SDB 的流行病学特征"。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.