Prevalence and Risk Factors of Age-Related Macular Degeneration in South Korea: Korea National Health and Nutrition Examination Survey.

IF 1.7 4区医学 Q3 OPHTHALMOLOGY

Ophthalmic epidemiology Pub Date : 2025-02-01 Epub Date: 2024-03-20 DOI:10.1080/09286586.2024.2321892

Mi Yeon Song, Yeji Kim, Kyungdo Han, Jae Hui Kim

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引用次数: 0

Abstract

Purpose: To evaluate the prevalence and risk factors of age-related macular degeneration (AMD) in the Korean population.

Methods: In this cross-sectional study based on the Korea National Health and Nutrition Examination Survey (2017-2020) data 13,737 participants aged ≥ 40 years with assessable fundus images were included. The prevalence and risk factors of AMD were evaluated. The prevalence of early AMD, geographic atrophy (GA), and neovascular AMD were also assessed. Logistic regression analyses were used to identify risk factors.

Results: The prevalence (95% confidence interval [CI]) of AMD was 13.94% (13.15-14.72). The prevalence (95% CI) of early AMD, GA, and neovascular AMD was 13.07% (12.29-13.85), 0.26% (0.17-0.35), and 0.61% (0.47-0.75), respectively. The prevalence increased with age; it was 3.61%, 11.33%, 20.31%, 31.37%, and 33.98% in participants in their 40s, 50s, 60s, 70s, and ≥ 80 years, respectively. In multivariate analysis, AMD was positively associated with older age (p < 0.001; odds ratio [OR], 1.08; 95% CI, 1.07-1.09), male sex (p = 0.014; OR, 1.27; 95% CI, 1.05-1.53), and lower degree of education (p < 0.001; OR, 1.36 (for junior high school graduates); 95% CI, 1.12-1.65).

Conclusions: AMD was detected in approximately one-third of individuals aged ≥ 70 years, thus indicating that AMD is a common disease among older Koreans. Regular fundus examinations in populations with risk factors for AMD as well as education on methods to prevent or delay AMD progression, such as the Mediterranean diet, are necessary.

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韩国老年性黄斑变性的患病率和风险因素：韩国国民健康与营养调查》。

目的：评估韩国人口中老年性黄斑变性（AMD）的患病率和风险因素：在这项基于韩国国民健康与营养调查（2017-2020 年）数据的横断面研究中，纳入了 13737 名年龄≥ 40 岁、具有可评估眼底图像的参与者。研究评估了AMD的患病率和风险因素。还评估了早期 AMD、地理萎缩（GA）和新生血管性 AMD 的患病率。采用逻辑回归分析确定风险因素：AMD的患病率（95%置信区间[CI]）为13.94%（13.15-14.72）。早期 AMD、GA 和新生血管性 AMD 的患病率（95% 置信区间）分别为 13.07% (12.29-13.85)、0.26% (0.17-0.35) 和 0.61% (0.47-0.75)。随着年龄的增长，患病率也在增加；在 40 多岁、50 多岁、60 多岁、70 多岁和≥ 80 岁的参与者中，患病率分别为 3.61%、11.33%、20.31%、31.37% 和 33.98%。在多变量分析中，AMD 与年龄较大（p p = 0.014；OR，1.27；95% CI，1.05-1.53）和受教育程度较低呈正相关（p 结论）：在年龄≥ 70 岁的人群中，约有三分之一的人被检测出患有老年黄斑变性，这表明老年黄斑变性是韩国老年人中的一种常见疾病。有必要对存在老年黄斑变性风险因素的人群进行定期眼底检查，并开展有关预防或延缓老年黄斑变性进展的方法（如地中海饮食）的教育。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ophthalmic epidemiology 医学-眼科学

CiteScore

3.70

自引率

5.60%

发文量

审稿时长

6-12 weeks

期刊介绍： Ophthalmic Epidemiology is dedicated to the publication of original research into eye and vision health in the fields of epidemiology, public health and the prevention of blindness. Ophthalmic Epidemiology publishes editorials, original research reports, systematic reviews and meta-analysis articles, brief communications and letters to the editor on all subjects related to ophthalmic epidemiology. A broad range of topics is suitable, such as: evaluating the risk of ocular diseases, general and specific study designs, screening program implementation and evaluation, eye health care access, delivery and outcomes, therapeutic efficacy or effectiveness, disease prognosis and quality of life, cost-benefit analysis, biostatistical theory and risk factor analysis. We are looking to expand our engagement with reports of international interest, including those regarding problems affecting developing countries, although reports from all over the world potentially are suitable. Clinical case reports, small case series (not enough for a cohort analysis) articles and animal research reports are not appropriate for this journal.