{"title":"Time Scale of Adaptation at the Tonal Sequence Processing in the Awake Mice Auditory Cortex Neurons","authors":"M. A. Egorova, A. G. Akimov, G. D. Khorunzhii","doi":"10.1134/s0022093024010241","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Abstract</h3><p>The study was first carried out on stimulus-specific adaptation\nof neurons in the primary and anterior fields of the awake house\nmice auditory cortex to sound sequences of four 100-ms tonal signals,\nwith a frequency of tones corresponding to the neuronal characteristic\nfrequency, and also with the inter-tone interval constant for one\nsequence and varying from 0 to 2000 ms in different sequences. The\nanalysis of the data obtained showed the adaptation effect in the\nresponses of all studied primary auditory cortex neurons, which\nwas observed as the absence or significant decrease in activity\nevoked by the components of a series of tones following the 1st,\nat inter-stimulus intervals of 0–500 ms. A quantitative assessment\nof the adaptation effects as a function of inter-stimulus intervals\nwithin the tonal sequence, performed over a whole population of\nstudied neurons, showed that the individual time scales of adaptation\nof neurons varied significantly, which may be crucial for the formation\nof optimal time windows for the processing of grouping and separation\nof sound events, which are important both for perception of animal vocalizations\nand human speech.</p>","PeriodicalId":15805,"journal":{"name":"Journal of Evolutionary Biochemistry and Physiology","volume":"26 1","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Evolutionary Biochemistry and Physiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1134/s0022093024010241","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The study was first carried out on stimulus-specific adaptation
of neurons in the primary and anterior fields of the awake house
mice auditory cortex to sound sequences of four 100-ms tonal signals,
with a frequency of tones corresponding to the neuronal characteristic
frequency, and also with the inter-tone interval constant for one
sequence and varying from 0 to 2000 ms in different sequences. The
analysis of the data obtained showed the adaptation effect in the
responses of all studied primary auditory cortex neurons, which
was observed as the absence or significant decrease in activity
evoked by the components of a series of tones following the 1st,
at inter-stimulus intervals of 0–500 ms. A quantitative assessment
of the adaptation effects as a function of inter-stimulus intervals
within the tonal sequence, performed over a whole population of
studied neurons, showed that the individual time scales of adaptation
of neurons varied significantly, which may be crucial for the formation
of optimal time windows for the processing of grouping and separation
of sound events, which are important both for perception of animal vocalizations
and human speech.
期刊介绍：
Journal of Evolutionary Biochemistry and Physiology publishes original experimental and theoretical and review articles related to evolution of the main forms of metabolism in connection with life origin; comparative and ontogenetic physiology and biochemistry, biochemical evolution of animal world; as well as evolution of functions; morphology, pharmacology, pathophysiology and ecological physiology. The journal welcomes manuscripts from all countries in the English or Russian language.
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