Practical Considerations When Choosing Chemoembolization versus Radioembolization for Hepatocellular Carcinoma.

IF 1 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Seminars in Interventional Radiology Pub Date : 2024-03-14 eCollection Date: 2024-02-01 DOI:10.1055/s-0044-1779714
Ashkan Heshmatzadeh Behzadi, Leila Haghani, Donna L D'Souza, Siobhan Flanagan, Christopher Jones
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引用次数: 0

Abstract

Transarterial chemoembolization (TACE) and transarterial radioembolization (TARE) are common liver-directed therapies (LDTs) for unresectable HCC. While both deliver intra-arterial treatment directly to the site of the tumor, they differ in mechanisms of action and side effects. Several studies have compared their side effect profile, time to progression, and overall survival data, but often these lack practical considerations when choosing which treatment modality to use. Many factors can impact operator's choice for treatment, and the choice depends on treatment availability, cost, insurance coverage, operator's comfort level, patient-specific factors, tumor location, tumor biology, and disease stage. This review discusses survival data, time to progression data, as well as more practical patient and tumor characteristics for personalized LDT with TACE or TARE.

选择化疗栓塞还是放射栓塞治疗肝细胞癌的实际考虑因素。
经动脉化疗栓塞术(TACE)和经动脉放射栓塞术(TARE)是治疗无法切除的肝癌的常见肝脏导向疗法(LDT)。虽然这两种疗法都能直接对肿瘤部位进行动脉内治疗,但它们的作用机制和副作用却各不相同。有几项研究比较了它们的副作用、进展时间和总生存期数据,但在选择使用哪种治疗方式时,这些研究往往缺乏实际考虑。许多因素都会影响操作者对治疗方法的选择,而选择取决于治疗方法的可用性、成本、保险范围、操作者的舒适度、患者特异性因素、肿瘤位置、肿瘤生物学特性和疾病分期。本综述讨论了使用 TACE 或 TARE 进行个性化 LDT 的生存数据、进展时间数据以及更实用的患者和肿瘤特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Seminars in Interventional Radiology
Seminars in Interventional Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING&nb-
CiteScore
1.90
自引率
7.10%
发文量
58
期刊介绍: Seminars in Interventional Radiology is a review journal that publishes topic-specific issues in the field of radiology and related sub-specialties. The journal provides comprehensive coverage of areas such as cardio-vascular imaging, oncologic interventional radiology, abdominal interventional radiology, ultrasound, MRI imaging, sonography, pediatric radiology, musculoskeletal radiology, metallic stents, renal intervention, angiography, neurointerventions, and CT fluoroscopy along with other areas. The journal''s content is suitable for both the practicing radiologist as well as residents in training.
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