A Versatile Elastin-Like Carrier for Bioactive Antimicrobial Peptide Production and Delivery

IF 4.4 4区医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Macromolecular bioscience Pub Date : 2024-03-14 DOI:10.1002/mabi.202470007

Laura Colomina – Alfaro, Paola Sist, Silvia Marchesan, Ranieri Urbani, Artemis Stamboulis, Antonella Bandiera

引用次数: 0

Abstract

Front Cover: The work described in article 2300236 by Antonella Bandiera and co-workers aims to develop antimicrobial coatings that reduce the likelihood of bacterial resistance. They report the production of a model human elastin-like polypeptide fusion with indolicidin showing good antimicrobial capacity. Coatings based on the elastin-like carrier alone (left) allow bacterial growth, whereas cell disruption occurs on surfaces coated with the fusion biopolymer (right).

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生产和输送生物活性抗菌肽的多功能弹性蛋白载体

封面：Antonella Bandiera 及其合作者在文章 2300236 中描述的工作旨在开发抗菌涂层，降低细菌产生抗药性的可能性。他们报告了一种与吲哚啶融合的人类弹性蛋白样多肽模型的生产情况，该模型显示出良好的抗菌能力。仅以弹性蛋白样载体为基础的涂层（左图）允许细菌生长，而在涂有融合生物聚合物的表面（右图）则会出现细胞破坏。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Macromolecular bioscience 生物-材料科学：生物材料

CiteScore

7.90

自引率

2.20%

发文量

211

审稿时长

1.5 months

期刊介绍： Macromolecular Bioscience is a leading journal at the intersection of polymer and materials sciences with life science and medicine. With an Impact Factor of 2.895 (2018 Journal Impact Factor, Journal Citation Reports (Clarivate Analytics, 2019)), it is currently ranked among the top biomaterials and polymer journals. Macromolecular Bioscience offers an attractive mixture of high-quality Reviews, Feature Articles, Communications, and Full Papers. With average reviewing times below 30 days, publication times of 2.5 months and listing in all major indices, including Medline, Macromolecular Bioscience is the journal of choice for your best contributions at the intersection of polymer and life sciences.