A Critical Review on the Long-Term COVID-19 Impacts on Patients With Diabetes

IF 2.5 3区医学 Q1 MEDICINE, GENERAL & INTERNAL

American Journal of Medicine Pub Date : 2025-02-01 DOI:10.1016/j.amjmed.2024.02.029

Sumel Ashique M.Pharm , Neeraj Mishra PhD , Ashish Garg PhD , Sweta Garg PhD , Arshad Farid PhD , Shweta Rai M.Pharm , Gaurav Gupta PhD , Kamal Dua PhD , Keshav Raj Paudel PhD , Farzad Taghizadeh-Hesary MD

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引用次数: 0

Abstract

Background

The world is currently grappling with the potentially life-threatening coronavirus disease 2019 (COVID-19), marking it as the most severe health crisis in the modern era. COVID-19 has led to a pandemic, with the World Health Organization (WHO) predicting that individuals with diabetes are at a higher risk of contracting the virus compared to the general population. This review aims to provide a practical summary of the long-term impacts of COVID-19 on patients with diabetes. Specifically, it focuses on the effects of SARS-CoV-2 on different types of diabetic patients, the associated mortality rate, the underlying mechanisms, related complications, and the role of vitamin D and zinc in therapeutic and preventive approaches.

Methods

Relevant literature was identified through searches on PubMed, Web of Science, and Science Direct in English, up to April 2023.

Results

COVID-19 can lead to distressing symptoms and pose a significant challenge for individuals living with diabetes. Older individuals and those with pre-existing conditions such as diabetes, coronary illness, and asthma are more susceptible to COVID-19 infection. Managing COVID-19 in individuals with diabetes presents challenges, as it not only complicates the fight against the infection but also potentially prolongs the recovery time. Moreover, the virus may thrive in individuals with high blood glucose levels. Various therapeutic approaches, including antidiabetic drugs, are available to help prevent COVID-19 in diabetic patients.

Conclusions

Diabetes increases the morbidity and mortality risk for patients with COVID-19. Efforts are globally underway to explore therapeutic interventions aimed at reducing the impact of diabetes on COVID-19.

查看原文本刊更多论文

关于 COVID-19 对糖尿病患者长期影响的批判性评论。

背景：目前，全世界都在努力应对可能危及生命的冠状病毒病 2019（COVID-19），这已成为当代最严重的健康危机。世界卫生组织（WHO）预测，与普通人群相比，糖尿病患者感染该病毒的风险更高。本综述旨在对 COVID-19 对糖尿病患者的长期影响进行实用性总结。具体而言，它侧重于 SARS-CoV-2 对不同类型糖尿病患者的影响、相关死亡率、潜在机制、相关并发症以及维生素 D 和锌在治疗和预防方法中的作用：方法：通过在PubMed、Web of Science和Science Direct上搜索到截至2023年4月的相关英文文献：COVID-19可导致令人痛苦的症状，并对糖尿病患者构成重大挑战。老年人和原有糖尿病、冠心病和哮喘等疾病的患者更容易感染COVID-19。管理 COVID-19 给糖尿病患者带来了挑战，因为这不仅会使抗感染变得复杂，还有可能延长康复时间。此外，病毒可能会在血糖水平较高的人群中大量繁殖。目前已有包括抗糖尿病药物在内的多种治疗方法帮助糖尿病患者预防 COVID-19：结论：糖尿病会增加 COVID-19 患者的发病率和死亡率。全球正在努力探索旨在减少糖尿病对 COVID-19 影响的治疗干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Medicine 医学-医学：内科

CiteScore

6.30

自引率

3.40%

发文量

449

审稿时长

9 days

期刊介绍： The American Journal of Medicine - "The Green Journal" - publishes original clinical research of interest to physicians in internal medicine, both in academia and community-based practice. AJM is the official journal of the Alliance for Academic Internal Medicine, a prestigious group comprising internal medicine department chairs at more than 125 medical schools across the U.S. Each issue carries useful reviews as well as seminal articles of immediate interest to the practicing physician, including peer-reviewed, original scientific studies that have direct clinical significance and position papers on health care issues, medical education, and public policy.