Multidrug-resistant tuberculosis: latest opinions on epidemiology, rapid diagnosis and management.

IF 2.8 3区医学 Q2 RESPIRATORY SYSTEM

Current Opinion in Pulmonary Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-15 DOI:10.1097/MCP.0000000000001070

Peter S Nyasulu, Cheick Oumar Doumbia, Veranyuy Ngah, Antieme Combo Georges Togo, Bassirou Diarra, Gershom Chongwe

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引用次数: 0

Abstract

Purpose of review: This review addresses the escalating global challenge of multidrug-resistant tuberculosis (MDR-TB) in Sub-Saharan Africa, with a focus on its complex comorbidity with HIV/AIDS. Emphasizing the urgency of the issue, the review aims to shed light on the unique healthcare landscape shaped by the convergence of high prevalence rates and intersecting complexities with HIV/AIDS in the region.

Recent findings: A notable increase in MDR-TB cases across Sub-Saharan Africa is attributed to challenges in timely diagnoses, treatment initiation, and patient treatment defaulting. The literature underscores the critical need for proactive measures to address diagnostic and treatment gaps associated with MDR-TB, particularly concerning its comorbidity with HIV/AIDS.

Summary: To effectively manage MDR-TB and its co-morbidity with HIV/AIDS, proactive screening programs are imperative. The review highlights the necessity of active follow-up strategies to ensure treatment adherence and reduce default rates, offering evidence-based insights for improved disease management in the region.

查看原文本刊更多论文

耐多药结核病：关于流行病学、快速诊断和管理的最新观点。

综述的目的：本综述探讨了撒哈拉以南非洲地区不断升级的耐多药结核病（MDR-TB）这一全球性挑战，重点关注其与艾滋病毒/艾滋病的复杂并发症。本综述强调了这一问题的紧迫性，旨在揭示该地区高发病率和与艾滋病毒/艾滋病相互交织的复杂性所形成的独特医疗保健格局：撒哈拉以南非洲地区的耐药结核病例明显增加，原因是在及时诊断、开始治疗和患者不接受治疗方面存在挑战。文献强调，亟需采取积极主动的措施，解决与 MDR-TB 相关的诊断和治疗差距问题，尤其是在 MDR-TB 与艾滋病毒/艾滋病并发症方面。摘要：为有效管理 MDR-TB 及其与艾滋病毒/艾滋病并发症，必须实施积极主动的筛查计划。这篇综述强调了积极的随访策略对确保坚持治疗和降低违约率的必要性，为改善该地区的疾病管理提供了循证见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Pulmonary Medicine 医学-呼吸系统

CiteScore

6.20

自引率

0.00%

发文量

109

审稿时长

6-12 weeks

期刊介绍： Current Opinion in Pulmonary Medicine is a highly regarded journal offering insightful editorials and on-the-mark invited reviews, covering key subjects such as asthma; cystic fibrosis; infectious diseases; diseases of the pleura; and sleep and respiratory neurobiology. Published bimonthly, each issue of Current Opinion in Pulmonary Medicine introduces world renowned guest editors and internationally recognized academics within the pulmonary field, delivering a widespread selection of expert assessments on the latest developments from the most recent literature.