Carbon-based composites in biomedical applications: a comprehensive review of properties, applications, and future directions

IF 23.2 2区 材料科学 Q1 MATERIALS SCIENCE, COMPOSITES
Choong-Hee Kim, Seul-Yi Lee, Kyong Yop Rhee, Soo-Jin Park
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Abstract

Carbon materials have emerged as a rapidly advancing category of high-performance materials that have garnered significant attention across various scientific and technological disciplines. Their exceptional biochemical properties render them highly suitable for diverse biomedical applications, including implantation, artificial joints, bioimaging, tissue and bone engineering, and scaffold fabrication. However, a more systematic approach is required to fully exploit the potential of carbon-based materials in the biomedical realm, necessitating extensive and collaborative research to address the existing challenges, which comprehensive long-term stability studies, the surface properties and investigate the toxicity of biomedical materials. This review paper aims to provide a comprehensive overview of carbon materials, elucidating their inherent advantages and highlighting their increasingly prominent role in biomedical applications. After a brief introduction of carbonaceous materials, we discuss innovative deposition strategies that can be utilized to artificially replicate desired properties, such as biocompatibility and toxicology, within complex structures. Further, this paper serves as a valuable resource to harness the potential of carbon materials in the realm of biomedical applications. Last, we conclude with a discussion on the significance of continuous exploration in propelling further advancements within this captivating field.

Abstract Image

生物医学应用中的碳基复合材料:特性、应用和未来发展方向综述
碳材料是一种发展迅速的高性能材料,在各个科学和技术学科中都备受关注。碳材料卓越的生物化学特性使其非常适合于各种生物医学应用,包括植入、人工关节、生物成像、组织和骨骼工程以及支架制造。然而,要充分挖掘碳基材料在生物医学领域的潜力,还需要更系统的方法,这就需要开展广泛的合作研究,以应对现有的挑战,其中包括全面的长期稳定性研究、表面特性和生物医学材料的毒性调查。本综述旨在全面概述碳材料,阐明其固有优势,并强调其在生物医学应用中日益突出的作用。在简要介绍了碳质材料之后,我们讨论了可用于在复杂结构中人工复制所需特性(如生物相容性和毒性)的创新沉积策略。此外,本文还是利用碳材料在生物医学应用领域的潜力的宝贵资源。最后,我们还讨论了不断探索对推动这一迷人领域进一步发展的重要意义。
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来源期刊
CiteScore
26.00
自引率
21.40%
发文量
185
期刊介绍: Advanced Composites and Hybrid Materials is a leading international journal that promotes interdisciplinary collaboration among materials scientists, engineers, chemists, biologists, and physicists working on composites, including nanocomposites. Our aim is to facilitate rapid scientific communication in this field. The journal publishes high-quality research on various aspects of composite materials, including materials design, surface and interface science/engineering, manufacturing, structure control, property design, device fabrication, and other applications. We also welcome simulation and modeling studies that are relevant to composites. Additionally, papers focusing on the relationship between fillers and the matrix are of particular interest. Our scope includes polymer, metal, and ceramic matrices, with a special emphasis on reviews and meta-analyses related to materials selection. We cover a wide range of topics, including transport properties, strategies for controlling interfaces and composition distribution, bottom-up assembly of nanocomposites, highly porous and high-density composites, electronic structure design, materials synergisms, and thermoelectric materials. Advanced Composites and Hybrid Materials follows a rigorous single-blind peer-review process to ensure the quality and integrity of the published work.
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