Safety and efficacy of ESD for laterally spreading tumors with hemorrhoids close to the dentate line.

IF 1.7 4区医学 Q2 SURGERY

Minimally Invasive Therapy & Allied Technologies Pub Date : 2024-08-01 Epub Date: 2024-03-13 DOI:10.1080/13645706.2024.2320380

Dongzi Peng, Xingcen Chen, Yuyong Tan, Liang Lv, Hongyi Zhu, Rong Li, Deliang Liu

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引用次数: 0

Abstract

Background: Endoscopic submucosal dissection (ESD) is a curative treatment for laterally spreading tumors (LSTs). However, the outcomes of ESD for LSTs with hemorrhoids remain largely unknown. Our study aimed to evaluate the usefulness of ESD in managing LSTs with hemorrhoids.

Material and methods: We retrospectively collected 418 consecutive LST patients treated with ESD between 2011 and 2023. A retrospective comparative analysis was conducted.

Results: There were 85 patients included in the hemorrhoids group and 333 patients included in the other group. The en-bloc resection rate, R0 resection rate, and curative resection rate were comparable in these two groups (p > 0.05). The LSTs with hemorrhoids have a significantly higher intraoperative bleeding rate during ESD when compared to the other group (12.9% vs. 5.4%, p = 0.028). Rates of intraoperative perforation and anal pain in the hemorrhoid group were significantly higher than those in the no-hemorrhoid group (2.4% vs. 0%, p = 0.041; 9.4% vs.0.6%, p < 0.001; respectively). Moreover, most of the related manifestations caused by hemorrhoids were relieved to various degrees after ESD.

Conclusions: ESD is a safe and effective treatment strategy for LSTs with hemorrhoids. A multi-center and prospective study should be conducted in the future to validate our results.

查看原文本刊更多论文

ESD治疗靠近齿状线的痔疮侧向扩散肿瘤的安全性和有效性。

背景：内镜下粘膜下剥离术（ESD）是治疗侧向扩散肿瘤（LST）的一种治愈性疗法。然而，ESD 治疗伴有痔疮的 LST 的效果在很大程度上仍不为人所知。我们的研究旨在评估ESD在治疗LST合并痔疮中的作用：我们回顾性地收集了2011年至2023年间接受ESD治疗的418例LST患者。我们进行了回顾性对比分析：结果：痔疮组有 85 名患者，其他组有 333 名患者。两组患者的全切率、R0切除率和治愈切除率相当（P>0.05）。与另一组相比，患有痔疮的 LST 患者在 ESD 期间的术中出血率明显更高（12.9% 对 5.4%，P = 0.028）。痔疮组的术中穿孔率和肛门疼痛率明显高于无痔疮组（2.4% 对 0%，P = 0.041；9.4% 对 0.6%，P 结论：ESD 是一种安全有效的治疗方法：对于患有痔疮的 LST 来说，ESD 是一种安全有效的治疗策略。今后应开展多中心前瞻性研究，以验证我们的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Minimally Invasive Therapy & Allied Technologies 医学-外科

CiteScore

3.80

自引率

5.90%

发文量

审稿时长

6-12 weeks

期刊介绍： Minimally Invasive Therapy and Allied Technologies (MITAT) is an international forum for endoscopic surgeons, interventional radiologists and industrial instrument manufacturers. It is the official journal of the Society for Medical Innovation and Technology (SMIT) whose membership includes representatives from a broad spectrum of medical specialities, instrument manufacturing and research. The journal brings the latest developments and innovations in minimally invasive therapy to its readers. What makes Minimally Invasive Therapy and Allied Technologies unique is that we publish one or two special issues each year, which are devoted to a specific theme. Key topics covered by the journal include: interventional radiology, endoscopic surgery, imaging technology, manipulators and robotics for surgery and education and training for MIS.