Chandan Chittapriya Sahu, Sourav Biswas, Renè Hommelsheim and Carsten Bolm
{"title":"Synthesis of α-ketothioamides with elemental sulfur under solvent-free conditions in a mixer mill†","authors":"Chandan Chittapriya Sahu, Sourav Biswas, Renè Hommelsheim and Carsten Bolm","doi":"10.1039/D3MR00025G","DOIUrl":null,"url":null,"abstract":"<p >A mechanochemical base-mediated synthesis of α-ketothioamide from readily available acetophenone derivatives is developed. The reaction is metal-free, solventless, and proceeds in a short reaction time. Importantly, the products differ from those formed under standard solution-based protocols.</p>","PeriodicalId":101140,"journal":{"name":"RSC Mechanochemistry","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2024/mr/d3mr00025g?page=search","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"RSC Mechanochemistry","FirstCategoryId":"1085","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2024/mr/d3mr00025g","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A mechanochemical base-mediated synthesis of α-ketothioamide from readily available acetophenone derivatives is developed. The reaction is metal-free, solventless, and proceeds in a short reaction time. Importantly, the products differ from those formed under standard solution-based protocols.