Novel presentation of a feline patient with visceral and cervical lymph node hemangiosarcoma.

IF 1.6 2区 农林科学 Q2 VETERINARY SCIENCES
Alexandra Goddard, Kristine Walters, Katy Campbell
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引用次数: 0

Abstract

Objective: To report a novel presentation of feline hemangiosarcoma.

Animals: A 14-year-old spayed female feline patient diagnosed with hemangiosarcoma of the spleen and a cervical lymph node.

Clinical presentation, progression, and procedures: The patient presented to the emergency service following a 1-week history of lethargy and hiding. Abdominal ultrasound revealed splenomegaly with multiple nodules and peritoneal fluid that was consistent with hemorrhagic effusion.

Treatment and outcome: The patient underwent a routine splenectomy and was started on doxorubicin. Histopathologic evaluation of the spleen confirmed visceral hemangiosarcoma. When the disease showed signs of progression, combination chemotherapy with cyclophosphamide and vincristine was initiated. Four months following presentation, a submandibular lymph node was removed and found to have metastatic hemangiosarcoma. From presentation to euthanasia, the patient survived 205 days.

Clinical relevance: Hemangiosarcoma is a rare cancer in feline patients, with a lack of veterinary literature on its presentation and chemotherapy protocols. The subject of this case report had a novel presentation of hemangiosarcoma and responded favorably to a chemotherapy protocol not previously described for this disease.

一名猫科动物内脏和颈淋巴结血管肉瘤患者的新病例。
动物报告猫血管肉瘤的一种新表现:14岁的绝育雌性猫科动物,被诊断为脾脏和颈淋巴结血管肉瘤:患者因嗜睡和躲藏一周后到急诊就诊。腹部超声波检查发现脾脏肿大并伴有多个结节,腹腔积液与出血性渗出一致:患者接受了常规脾脏切除术,并开始服用多柔比星。脾脏组织病理学评估证实为内脏血管肉瘤。当病情出现进展迹象时,患者开始接受环磷酰胺和长春新碱联合化疗。发病四个月后,切除了一个颌下淋巴结,发现该淋巴结为转移性血管肉瘤。从发病到安乐死,患者存活了205天:血管肉瘤在猫科动物中是一种罕见的癌症,有关这种癌症的表现和化疗方案的兽医文献十分匮乏。本病例报告中的患者是一种表现形式新颖的血管肉瘤,并且对以前未曾描述过的化疗方案反应良好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.60
自引率
15.80%
发文量
539
审稿时长
6-16 weeks
期刊介绍: Published twice monthly, this peer-reviewed, general scientific journal provides reports of clinical research, feature articles and regular columns of interest to veterinarians in private and public practice. The News and Classified Ad sections are posted online 10 days to two weeks before they are delivered in print.
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