Risk factors for cognitive impairment in patients with chronic kidney disease.

IF 3.9 4区 医学 Q1 PSYCHIATRY
Xiao-Hui Wang, Yong He, Huan Zhou, Ting Xiao, Ran Du, Xin Zhang
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引用次数: 0

Abstract

Background: Chronic kidney disease (CKD) patients have been found to be at risk of concurrent cognitive dysfunction in previous studies, which has now become an important public health issue of widespread concern.

Aim: To investigate the risk factors for concurrent cognitive dysfunction in patients with CKD.

Methods: This is a prospective cohort study conducted among patients with CKD between October 2021 and March 2023. A questionnaire was formulated by literature review and expert consultation and included questions about age, sex, education level, per capita monthly household income, marital status, living condition, payment method, and hypertension.

Results: Logistic regression analysis showed that patients aged 60-79 years [odds ratio (OR) = 1.561, P = 0.015] and ≥ 80 years (OR = 1.760, P = 0.013), participants with middle to high school education (OR = 0.820, P = 0.027), divorced or widowed individuals (OR = 1.37, P = 0.032), self-funded patients (OR = 2.368, P = 0.008), and patients with hypertension (OR = 2.011, P = 0.041) had a higher risk of cognitive impairment. The risk of cognitive impairment was lower for those with a college degree (OR = 0.435, P = 0.034) and married individuals.

Conclusion: The risk factors affecting cognitive dysfunction are age, 60-79 years and ≥ 80 years; education, primary school education or less; marital status, divorced or widowed; payment method, self-funded; hypertension; and CKD.

慢性肾病患者认知障碍的风险因素。
背景:目的:研究慢性肾脏病(CKD)患者并发认知功能障碍的风险因素:这是一项前瞻性队列研究,研究对象为 2021 年 10 月至 2023 年 3 月期间的慢性肾脏病患者。通过文献回顾和专家咨询制定了一份调查问卷,内容包括年龄、性别、教育程度、家庭人均月收入、婚姻状况、生活状况、支付方式和高血压等问题:逻辑回归分析显示,年龄在 60-79 岁[几率比(OR)= 1.561,P=0.015]和≥80 岁(OR=1.760,P=0.013)、初中至高中教育程度(OR=0.820,P=0.027)、离婚或丧偶者(OR = 1.37,P = 0.032)、自费患者(OR = 2.368,P = 0.008)和高血压患者(OR = 2.011,P = 0.041)发生认知障碍的风险更高。具有大学学历(OR = 0.435,P = 0.034)和已婚者的认知障碍风险较低:结论:影响认知功能障碍的风险因素包括年龄(60-79 岁和≥80 岁)、教育程度(小学或以下)、婚姻状况(离婚或丧偶)、支付方式(自费)、高血压和慢性肾脏病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
自引率
6.50%
发文量
110
期刊介绍: The World Journal of Psychiatry (WJP) is a high-quality, peer reviewed, open-access journal. The primary task of WJP is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of psychiatry. In order to promote productive academic communication, the peer review process for the WJP is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJP are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in psychiatry.
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