Application of the Sleep C.A.L.M. Tool for Assessing Nocturia in a Large Nationally Representative Cohort.

IF 1.8 3区医学 Q3 UROLOGY & NEPHROLOGY

International Neurourology Journal Pub Date : 2024-02-01 Epub Date: 2024-02-29 DOI:10.5213/inj.2346258.129

Joseph U Boroda, Benjamin De Leon, Lakshay Khosla, Muchi D Chobufo, Syed N Rahman, Jason M Lazar, Jeffrey P Weiss, Thomas F Monaghan

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引用次数: 0

Abstract

Purpose: Nocturia significantly impacts patients' quality of life but remains insufficiently evaluated and treated. The "Sleep C.A.L.M." system categorizes the factors thought to collectively reflect most underlying causes of nocturia (Sleep disorders, Comorbidities, Actions [i.e., modifiable patient behaviors such as excess fluid intake], Lower urinary tract dysfunction, and Medications). The purpose of this study was to assess the association of nocturia with the Sleep C.A.L.M. categories using a nationally representative dataset.

Methods: Retrospective analysis of the National Health and Nutrition Examination Survey from 2013/14-2017/18 cycles was conducted. Pertinent questionnaire, laboratory, dietary, and physical examination data were used to ascertain the presence of Sleep C.A.L.M. categories in adults ≥20 years of age. Nocturia was defined as ≥2 nighttime voids.

Results: A total of 12,274 included subjects were included (51.6% female; median age, 49.0 years [interquartile range, 34.0-62.0 years]; 27.6% nocturia). Among subjects with nocturia, the prevalence of 0, ≥1, and ≥2 Sleep C.A.L.M. categories was 3.5% (95% confidence interval [CI], 2.8%-4.4%), 96.5% (95% CI, 95.6%-97.2%), and 81.2% (95% CI, 78.9%-83.3%), respectively. Compared to those with 0-1 Sleep C.A.L.M. categories, the adjusted odds of nocturia in subjects with 2, 3, and 4-5 Sleep C. A.L.M. categories were 1.77 (95% CI, 1.43-2.21), 2.33 (1.89-2.87), and 3.49 (2.81-4.35), respectively (P<0.001). Similar trends were observed for most age and sex subgroups. When assessed individually, each of the 5 Sleep C.A.L.M. categories were independently associated with greater odds of nocturia, which likewise persisted across multiple age and sex subgroups.

Conclusion: Sleep C.A.L.M. burden is associated with increased odds of nocturia in a dose-dependent fashion, and potentially a relevant means by which to organize the underlying etiologies for nocturia among community-dwelling adults.

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应用睡眠 C.A.L.M.工具评估具有全国代表性的大型群组中的夜尿症。

目的：夜尿症严重影响患者的生活质量，但对其评估和治疗仍然不足。睡眠 C.A.L.M. "系统对被认为能共同反映夜尿症大多数根本原因的因素进行了分类（睡眠障碍、并发症、行动[即可改变的患者行为，如摄入过多液体]、下尿路功能障碍和药物）。本研究的目的是利用具有全国代表性的数据集评估夜尿症与睡眠 C.A.L.M. 类别之间的关联：方法：对 2013/14-2017/18 年周期的国家健康与营养调查进行回顾性分析。使用相关的问卷、实验室、饮食和体检数据来确定年龄≥20 岁的成年人是否存在睡眠 C.A.L.M. 类别。夜尿定义为夜间排尿次数≥2次：共纳入了 12 274 名受试者（51.6% 为女性；中位年龄为 49.0 岁[四分位间范围为 34.0-62.0 岁]；27.6% 有夜尿症）。在夜尿症患者中，睡眠C.A.L.M.类别为0、≥1和≥2的患病率分别为3.5%（95%置信区间[CI]，2.8%-4.4%）、96.5%（95% CI，95.6%-97.2%）和81.2%（95% CI，78.9%-83.3%）。与睡眠C.A.L.M.类别为0-1的受试者相比，睡眠C.A.L.M.类别为2、3和4-5的受试者出现夜尿的调整后几率分别为1.77（95% CI，1.43-2.21）、2.33（1.89-2.87）和3.49（2.81-4.35）（PConclusion：睡眠C.A.L.M.负担与夜尿症发生几率的增加呈剂量依赖关系，有可能成为组织社区居住成年人夜尿症潜在病因的一种相关手段。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Neurourology Journal UROLOGY & NEPHROLOGY-

CiteScore

4.40

自引率

21.70%

发文量

审稿时长

4 weeks

期刊介绍： The International Neurourology Journal (Int Neurourol J, INJ) is a quarterly international journal that publishes high-quality research papers that provide the most significant and promising achievements in the fields of clinical neurourology and fundamental science. Specifically, fundamental science includes the most influential research papers from all fields of science and technology, revolutionizing what physicians and researchers practicing the art of neurourology worldwide know. Thus, we welcome valuable basic research articles to introduce cutting-edge translational research of fundamental sciences to clinical neurourology. In the editorials, urologists will present their perspectives on these articles. The original mission statement of the INJ was published on October 12, 1997. INJ provides authors a fast review of their work and makes a decision in an average of three to four weeks of receiving submissions. If accepted, articles are posted online in fully citable form. Supplementary issues will be published interim to quarterlies, as necessary, to fully allow berth to accept and publish relevant articles.