Endoscopic resection for calcifying fibrous tumors of the gastrointestinal tract.

IF 2.6 Q3 ONCOLOGY

World journal of clinical oncology Pub Date : 2024-02-24 DOI:10.5306/wjco.v15.i2.282

Zi-Han Geng, Yan Zhu, Pei-Yao Fu, Yi-Fan Qu, Shi-Yao Chen, Yun-Shi Zhong, Yi-Qun Zhang, Wei-Feng Chen, Wen-Zheng Qin, Jian-Wei Hu, Ming-Yan Cai, Li-Qing Yao, Quan-Lin Li, Ping-Hong Zhou

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引用次数: 0

Abstract

Background: Calcifying fibrous tumors (CFTs) are rare mesenchymal lesions that can occur in various sites throughout the body, including the tubular gastrointestinal (GI) tract.

Aim: To analyze the clinical findings of 36 patients with GI tract CFTs to provide guidance for diagnosis and treatment.

Methods: This retrospective study included 36 patients diagnosed with CFTs of the GI tract. We collected demographic and clinical information and conducted regular follow-ups to assess for local recurrence.

Results: The stomach was the most commonly involved site, accounting for 72.2% of the 36 CFTs. Endoscopic mucosal resection (n = 1, 2.8%), endoscopic submucosal dissection (n = 14, 38.9%), endoscopic full-thickness resection (n = 16, 44.4%), and submucosal tunneling endoscopic resection (n = 5, 13.9%) were used to resect calcifying fibrous tumors. Overall, 34 (94.4%) CFTs underwent complete endoscopic resections with a mean procedure time of 39.8 ± 29.8 min. The average maximum diameter of the tumors was 10.6 ± 4.3 cm. No complications, such as bleeding or perforation, occurred during an average hospital stay of 2.9 ± 1.2 d. In addition, two patients developed new growth of CFTs near the primary tumor sites, and none of the patients developed distant metastases during the follow-up period.

Conclusion: GI tract CFTs are rare and typically benign tumors that can be effectively managed with endoscopic procedures.

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消化道钙化纤维瘤的内窥镜切除术。

背景：钙化纤维性肿瘤（CFTs）是一种罕见的间质病变，可发生在全身各个部位，包括管状胃肠道（GI）。目的：分析36例胃肠道CFTs患者的临床表现，为诊断和治疗提供指导：这项回顾性研究纳入了 36 名确诊为消化道 CFT 的患者。我们收集了人口统计学和临床信息，并进行定期随访以评估局部复发情况：胃是最常受累的部位，占 36 例 CFT 的 72.2%。切除钙化纤维性肿瘤的方法有内镜下粘膜切除术（1例，2.8%）、内镜下粘膜下剥离术（14例，38.9%）、内镜下全层切除术（16例，44.4%）和粘膜下隧道内镜切除术（5例，13.9%）。总体而言，34 例（94.4%）钙化纤维瘤接受了完整的内镜切除，平均手术时间为 39.8 ± 29.8 分钟。肿瘤的平均最大直径为（10.6 ± 4.3）厘米。平均住院时间为（2.9±1.2）天，未发生出血或穿孔等并发症。此外，有两名患者在原发肿瘤部位附近出现了新的CFT生长，随访期间没有一名患者出现远处转移：结论：消化道CFT是罕见的典型良性肿瘤，可通过内窥镜手术进行有效治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

World journal of clinical oncology ONCOLOGY-

自引率

0.00%

发文量

585

期刊介绍： The WJCO is a high-quality, peer reviewed, open-access journal. The primary task of WJCO is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of oncology. In order to promote productive academic communication, the peer review process for the WJCO is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCO are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in oncology. Scope: Art of Oncology, Biology of Neoplasia, Breast Cancer, Cancer Prevention and Control, Cancer-Related Complications, Diagnosis in Oncology, Gastrointestinal Cancer, Genetic Testing For Cancer, Gynecologic Cancer, Head and Neck Cancer, Hematologic Malignancy, Lung Cancer, Melanoma, Molecular Oncology, Neurooncology, Palliative and Supportive Care, Pediatric Oncology, Surgical Oncology, Translational Oncology, and Urologic Oncology.